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AKR1B10 cdna clone

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Catalog # MBS1273450
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
AKR1B10 cdna clone
Product Name

AKR1B10, cDNA Clone

Popular Item
Also Known As

AKR1B10 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
951
Sequence
atggccacgt ttgtggagct cagtaccaaa gccaagatgc ccattgtggg cctgggcact tggaagtctc ctcttggcaa agtgaaagaa gcagtgaagg tggccattga tgcaggatat cggcacattg actgtgccta tgtctatcag aatgaacatg aagtggggga agccatccaa gagaagatcc aagagaaggc tgtgaagcgg gaggacctgt tcatcgtcag caagttgtgg cccactttct ttgagagacc ccttgtgagg aaagcctttg agaagaccct caaggacctg aagctgagct atctggacgt ctatcttatt cactggccac agggattcaa gtctggggat gaccttttcc ccaaagatga taaaggtaat gccatcggtg gaaaagcaac gttcttggat gcctgggagg ccatggagga gctggtggat gaggggctgg tgaaagccct tggggtctcc aatttcagcc acttccagat cgagaagctc ttgaacaaac ctggactgaa atataaacca gtgactaacc aggttgagtg tcacccatac ctcacacagg agaaactgat ccagtactgc cactccaagg gcatcaccgt tacggcctac agccccctgg gctctccgga tagaccttgg gccaagccag aagacccttc cctgctggag gatcccaaga ttaaggagat tgctgcaaag cacaaaaaaa ccgcagccca ggttctgatc cgtttccata tccagaggaa tgtgattgtc atccccaagt ctgtgacacc agcacgcatt gttgagaaca ttcaggtctt tgactttaaa ttgagtgatg aggagatggc aaccatactc agcttcaaca gaaactggag ggcctgtaac gtgttgcaat cctctcattt ggaagactat cccttcgatg cagaatattg a
OMIM
604707
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of AKR1B10 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AKR1B10. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,020 Da
NCBI Official Full Name
Homo sapiens aldo-keto reductase family 1, member B10 (aldose reductase), mRNA
NCBI Official Synonym Full Names
aldo-keto reductase family 1 member B10
NCBI Official Symbol
AKR1B10  [Similar Products]
NCBI Official Synonym Symbols
HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12
  [Similar Products]
NCBI Protein Information
aldo-keto reductase family 1 member B10
UniProt Protein Name
Aldo-keto reductase family 1 member B10
UniProt Synonym Protein Names
ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase
UniProt Gene Name
AKR1B10  [Similar Products]
UniProt Synonym Gene Names
AKR1B11; ARP; hARP; SI reductase  [Similar Products]
UniProt Entry Name
AK1BA_HUMAN
NCBI Summary for AKR1B10
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for AKR1B10
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.-; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.21; Lipid Metabolism - linoleic acid; Carbohydrate Metabolism - butanoate; Oxidoreductase

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytosol

Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; retinoid metabolic process; steroid metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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