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AKR7A2 recombinant protein :: Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) Recombinant Protein

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Catalog # MBS1003588
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $770 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $865 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,030 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,095 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,135 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,170 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,325 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,335 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,580 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,715 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,060 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,100 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,165 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,185 +3 FREE 8GB USB
AKR7A2 recombinant protein
Product Name

Aflatoxin B1 aldehyde reductase member 2 (AKR7A2), Recombinant Protein

Full Product Name

Recombinant Human Aflatoxin B1 aldehyde reductase member 2 (AKR7A2)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-359aa, Full length protein
Sequence
MLSAASRVVS RAAVHCALRS PPPEARALAM SRPPPPRVAS VLGTMEMGRR MDAPASAAAV RAFLERGHTE LDTAFMYSDG QSETILGGLG LGLGGGDCRV KIATKANPWD GKSLKPDSVR SQLETSLKRL QCPQVDLFYL HAPDHGTPVE ETLHACQRLH QEGKFVELGL SNYASWEVAE ICTLCKSNGW ILPTVYQGMY NATTRQVETE LFPCLRHFGL RFYAYNPLAG GLLTGKYKYE DKDGKQPVGR FFGNSWAETY RNRFWKEHHF EAIALVEKAL QAAYGASAPS VTSAALRWMY HHSQLQGAHG DAVILGMSSL EQLEQNLAAT EEGPLEPAVV DAFNQAWHLV AHECPNYFR
OMIM
603418
3D Structure
ModBase 3D Structure for O43488
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AKR7A2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AKR7A2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,589 Da
NCBI Official Full Name
aflatoxin B1 aldehyde reductase member 2 isoform 1
NCBI Official Synonym Full Names
aldo-keto reductase family 7 member A2
NCBI Official Symbol
AKR7A2  [Similar Products]
NCBI Official Synonym Symbols
AFAR; AKR7; AFAR1; AFB1-AR1
  [Similar Products]
NCBI Protein Information
aflatoxin B1 aldehyde reductase member 2
UniProt Protein Name
Aflatoxin B1 aldehyde reductase member 2
UniProt Synonym Protein Names
AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; SSA reductase
UniProt Gene Name
AKR7A2  [Similar Products]
UniProt Synonym Gene Names
AFAR; AFAR1; AKR7; AFB1-AR 1; SSA reductase  [Similar Products]
NCBI Summary for AKR7A2
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
UniProt Comments for AKR7A2
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Research Articles on AKR7A2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with AKR7A2 recombinant protein
 Reference Product  PubMed Publications
 AKR7A3 recombinant protein  >3 publications with AKR7A2 and AKR7A3
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