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Alox12 recombinant protein :: Arachidonate 12-lipoxygenase, 12S-type (Alox12) Recombinant Protein

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Catalog # MBS964127
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $1,115 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,350 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,470 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,520 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,590 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,625 +2 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,720 +2 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,955 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,460 +3 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,510 +3 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,545 +3 FREE 8GB USB
  1 mg (Yeast)  /  $2,710 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,880 +4 FREE 8GB USB
Alox12 recombinant protein
Product Name

Arachidonate 12-lipoxygenase, 12S-type (Alox12), Recombinant Protein

Full Product Name

Recombinant Mouse Arachidonate 12-lipoxygenase, 12S-type (Alox12)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-663aa, Full length protein
Sequence
MGRYRVRVVT GAWLFSGSLN LVRLWLVGEH REAKLELQLR PARGKEEEFD FDVPEDLGPL QFVKLHKQHT VVDDAWFCNL ITVQGPGTSA EAVFPCYRWV QGEGILSLPE GTARLAGDNA LDVFQKYREK ELKERQQTYC WATWKEGLPQ TIAADCKDDL PPNMRFHEEK RLDFEWTLKA GVLEMGLKRV YTLLRSWNHL EDFDQIFWGQ KSALAEKVHQ CWQEDELFGY QFLNGANPML LRRSTSLPSR LVLPSGMEEL QAQLEKELKN GSLFEADFIL LDGIPANVIR GEPQYLAAPL VMLRMDPGGK LLPMAIQIQP PNPSSPAPTL FLPSDPPLAW LLAKIWVRNS DFQLQELQFH LLNTHLVAEV IAVATMRCLP GLHPIFKLLV PHIRYTMEIN TRSRTQLISD GGIFDQVVST GGGGHVQLLT RAVAQLTYHS LCPPDDLANR GLLRIPSALY ARDALQLWEV TARYVKGMVH LFYQSDDIVR GDPELQAWCR EITEVGLCHA QDRGFPVSFQ SRAQLCHFLT MCVFTCTAQH AAINQGQLDW YGWVPNAPCT MRMPPPTSKD DVTMETVMGS LPDVQKACLQ MTITWHLGRL QPDMVPLGHH TEKYFSDPRT KAVLSQFQAD LDNLEKEITA RNEQLDLPYE YLKPSRIENS ITI
3D Structure
ModBase 3D Structure for P39655
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Alox12 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Alox12. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,390 Da
NCBI Official Full Name
arachidonate 12-lipoxygenase, 12S-type isoform 2
NCBI Official Synonym Full Names
arachidonate 12-lipoxygenase
NCBI Official Symbol
Alox12  [Similar Products]
NCBI Official Synonym Symbols
P-12LO; Alox12p; 9930022G08Rik
  [Similar Products]
NCBI Protein Information
arachidonate 12-lipoxygenase, 12S-type
UniProt Protein Name
Arachidonate 12-lipoxygenase, 12S-type
UniProt Synonym Protein Names
Lipoxin synthase 12-LO (EC:3.3.2.-); Platelet-type lipoxygenase 12; P-12LO
UniProt Gene Name
Alox12  [Similar Products]
UniProt Synonym Gene Names
Alox12p; 12S-LOX; 12S-lipoxygenase; P-12LO  [Similar Products]
UniProt Comments for Alox12
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with Alox12 recombinant protein
 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with Alox12 and FLNA
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