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Alox5 recombinant protein :: Arachidonate 5-lipoxygenase (Alox5) Recombinant Protein

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Catalog # MBS948437
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $1,125 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,360 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,490 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,530 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,600 +2 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,640 +2 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,735 +2 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,970 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,490 +3 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,525 +3 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,560 +3 FREE 8GB USB
  1 mg (Yeast)  /  $2,735 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,905 +4 FREE 8GB USB
Alox5 recombinant protein
Product Name

Arachidonate 5-lipoxygenase (Alox5), Recombinant Protein

Full Product Name

Recombinant Mouse Arachidonate 5-lipoxygenase (Alox5)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-674aa, Full length protein
Sequence
MPSYTVTVAT GSQWFAGTDD YIYLSLIGSA GCSEKHLLDK AFYNDFERGA VDSYDVTVDE ELGEIYLVKI EKRKYWLHDD WYLKYITLKT PHGDYIEFPC YRWITGEGEI VLRDGRAKLA RDDQIHILKQ HRRKELEARQ KQYRWMEWNP GFPLSIDAKC HKDLPRDIQF DSEKGVDFVL NYSKAMENLF INRFMHMFQS SWHDFADFEK IFVKISNTIS ERVKNHWQED LMFGYQFLNG CNPVLIKRCT ALPPKLPVTT EMVECSLERQ LSLEQEVQEG NIFIVDYELL DGIDANKTDP CTHQFLAAPI CLLYKNLANK IVPIAIQLNQ TPGESNPIFL PTDSKYDWLL AKIWVRSSDF HVHQTITHLL RTHLVSEVFG IAMYRQLPAV HPLFKLLVAH VRFTIAINTK AREQLICEYG LFDKANATGG GGHVQMVQRA VQDLTYSSLC FPEAIKARGM DSTEDIPFYF YRDDGLLVWE AIQSFTMEVV SIYYENDQVV EEDQELQDFV KDVYVYGMRG KKASGFPKSI KSREKLSEYL TVVIFTASAQ HAAVNFGQYD WCSWIPNAPP TMRAPPPTAK GVVTIEQIVD TLPDRGRSCW HLGAVWALSQ FQENELFLGM YPEEHFIEKP VKEAMIRFRK NLEAIVSVIA ERNKNKKLPY YYLSPDRIPN SVAI
3D Structure
ModBase 3D Structure for P48999
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Alox5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Alox5 recombinant protein
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
NCBI/Uniprot data below describe general gene information for Alox5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
77,967 Da
NCBI Official Full Name
arachidonate 5-lipoxygenase
NCBI Official Synonym Full Names
arachidonate 5-lipoxygenase
NCBI Official Symbol
Alox5  [Similar Products]
NCBI Official Synonym Symbols
5LO; 5LX; 5-LO; 5-LOX; AI850497; F730011J02
  [Similar Products]
NCBI Protein Information
arachidonate 5-lipoxygenase
UniProt Protein Name
Arachidonate 5-lipoxygenase
UniProt Gene Name
Alox5  [Similar Products]
UniProt Synonym Gene Names
5-LO; 5-lipoxygenase  [Similar Products]
UniProt Comments for Alox5
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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