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alphaCTx elisa kit :: Porcine Alpha-Crosslaps ELISA Kit

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Catalog # MBS052598
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
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alphaCTx elisa kit
Product Name

Alpha-Crosslaps (alphaCTx), ELISA Kit

Full Product Name

Porcine Alpha-Crosslaps ELISA Kit

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for P13395
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of alphaCTx elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for alphaCTxpurchase
MBS052598 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Alpha-Crosslaps (alphaCTx) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing alphaCTx. The ELISA analytical biochemical technique of the MBS052598 kit is based on alphaCTx antibody-alphaCTx antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect alphaCTx antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, alphaCTx. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for alphaCTx. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
278,303 Da
NCBI Official Full Name
alpha spectrin, isoform D
NCBI Official Synonym Full Names
alpha Spectrin
NCBI Official Symbol
alpha-Spec  [Similar Products]
NCBI Official Synonym Symbols
3A9; alfa-Spec; alpha; alpha-Sp; alpha-Spc; alpha-Spe; alpha-spec; alpha-SPEC; alpha-Spect; alpha-spectrin; alpha-Spectrin; alphaSp; alphaSpec; alphaSpectrin; anon-EST:fe2E2; CG1977; DmelCG1977; dre3; FBtr0072789; FCP-B; klo; l(3)04276; l(3)62Bd; l(3)alph
  [Similar Products]
NCBI Protein Information
CG1977 gene product from transcript CG1977-RA; CG1977-PA; CG1977-PB; CG1977-PC; CG1977-PD; aSpc 3A9; alpha spectrin; alpha-SPECTRIN; alpha-Spec-PA; alpha-Spec-PB; alpha-Spec-PC; alpha-Spec-PD; alpha-spectrin II; alphaSpectrin; anon-fast-evolving-2E2; klotzchen
UniProt Protein Name
Spectrin alpha chain
UniProt Gene Name
alpha-Spec  [Similar Products]
UniProt Synonym Gene Names
SPEC-A  [Similar Products]
UniProt Entry Name
SPTCA_DROME
UniProt Comments for alphaCTx
Function: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization. Ref.5 Ref.7 Ref.8

Subunit structure: Native spectrin molecule is a tetramer composed of two antiparallel heterodimers joined head to head so that each end of the native molecule includes the C-terminus of the alpha subunit and the N-terminus of the beta subunit. Interacts with calmodulin in a calcium-dependent manner, interacts with F-actin and also interacts with Lva. Interacts with Ten-m. Ref.8 Ref.13

Subcellular location: Cytoplasm › cytoskeleton. Golgi apparatus. Note: Near the inner surface of the plasma membrane of nearly all cells. Lva-alpha-spectrin complexes are found at the Golgi. Ref.8

Tissue specificity: A substantial pool of maternal protein in the egg undergoes dynamic changes in distribution early in embryogenesis. In gastrulated embryo, the highest level of protein is found in the respiratory tract cells and the lowest in parts of the forming gut. Ref.9

Developmental stage: Expressed both maternally and zygotically.

Miscellaneous: Its transcript shares the first untranslated exon with the dlt transcript, suggesting a common regulation.

Sequence similarities: Belongs to the spectrin family.Contains 2 EF-hand domains.Contains 1 SH3 domain.Contains 22 spectrin repeats.

Sequence caution: The sequence AAL39886.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence ABA81823.1 differs from that shown. Reason: Frameshift at position 1549.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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