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AMACR cdna clone

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Catalog # MBS1273980
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
AMACR cdna clone
Product Name

AMACR, cDNA Clone

Popular Item
Full Product Name

AMACR cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcactgc agggcatctc ggtcatggag ctgtccggcc tggccccggg cccgttctgt gctatggtcc tggctgactt cggggcgcgt gtggtacgcg tggaccggcc cggctcccgc tacgacgtga gccgcttggg ccggggcaag cgctcgctag tgctggacct gaagcagccg cggggagccg ccgtgctgcg gcgtctgtgc aagcggtcgg atgtgctgct ggagcccttc cgccgcggtg tcatggagaa actccagctg ggcccagaga ttctgcagcg ggaaaatcca aggcttattt atgccaggct gagtggattt ggccagtcag gaagcttctg ccggttagct ggccacgata tcaactattt ggctttgtca ggtggaagga acagcatatt taagttcttt tctgtggaaa actcagaaat cgagtctgtg ggaagcacct cgaggacaga acatgttgga tggtggagca cctttctata cgacttacag gacagcagat ggggaattca tggctgttgg agcaatagaa ccccagttct acgagctgct gatcaaagga cttggactaa agtctga
OMIM
214950
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of AMACR cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AMACR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,860 Da
NCBI Official Full Name
Homo sapiens alpha-methylacyl-CoA racemase, mRNA
NCBI Official Synonym Full Names
alpha-methylacyl-CoA racemase
NCBI Official Symbol
AMACR  [Similar Products]
NCBI Official Synonym Symbols
RM; RACE; CBAS4; AMACRD
  [Similar Products]
NCBI Protein Information
alpha-methylacyl-CoA racemase
UniProt Protein Name
Alpha-methylacyl-CoA racemase
UniProt Synonym Protein Names
2-methylacyl-CoA racemase
UniProt Gene Name
AMACR  [Similar Products]
UniProt Entry Name
AMACR_HUMAN
NCBI Summary for AMACR
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
UniProt Comments for AMACR
AMACR: Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Belongs to the CaiB/BaiF CoA-transferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.1.99.4; Isomerase; Lipid Metabolism - primary bile acid biosynthesis; Mitochondrial

Chromosomal Location of Human Ortholog: 5p13

Cellular Component: cytoplasm; mitochondrion; peroxisomal matrix; peroxisome

Molecular Function: alpha-methylacyl-CoA racemase activity; receptor binding

Biological Process: bile acid biosynthetic process; bile acid metabolic process; fatty acid beta-oxidation using acyl-CoA oxidase

Disease: Alpha-methylacyl-coa Racemase Deficiency; Bile Acid Synthesis Defect, Congenital, 4
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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