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AMBP antigen :: Alpha-1-microglobulin Antigen

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Catalog # MBS7041626
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AMBP antigen
Product Name

Alpha-1-microglobulin (AMBP), Antigen

Popular Item
Full Product Name

Human Alpha-1-microglobulin protein

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
176870
3D Structure
ModBase 3D Structure for P02760
Host
Yeast
Purity/Purification
>95% by SDS-PAGE
Form/Format
Supplied in liquid form in 20 mM Tris, 500 mM NaCl, pH 8.0, 50% glycerol
Tag
His-tagged
Activity
Protein concentration is determined >1mg/ml by commercial A1M Assay Kit by Latex
Note
Applications are user defined. Product is developed as raw material and quality control tested in house, data is not provided on the data sheet. The researcher needs to establish and confirm the suitability of the product for their application.

Testing data may be available for this product regarding applications and assays the lab developed, please inquire.
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
Other Notes
Small volumes of AMBP antigen vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for AMBP antigen
Applications Tested/Suitable for AMBP antigen
ELISA (EIA), Latex Enhanced Turbidimetricimmunoassay (LETIA), Calibrator, Immunogen and other possible application.
NCBI/Uniprot data below describe general gene information for AMBP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,999 Da
NCBI Official Full Name
alpha-1-microglobulin, partial
NCBI Official Synonym Full Names
alpha-1-microglobulin/bikunin precursor
NCBI Official Symbol
NCBI Official Synonym Symbols
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
  [Similar Products]
NCBI Protein Information
protein AMBP
UniProt Protein Name
Protein AMBP
UniProt Synonym Protein Names
Alpha-1-microglobulin; Protein HC
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
HCP; ITIL; Protein HC; ITI-LC  [Similar Products]
UniProt Entry Name
AMBP_HUMAN
NCBI Summary for AMBP
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
UniProt Comments for AMBP
AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: cell surface; extracellular region; extracellular space; intracellular membrane-bound organelle; plasma membrane

Molecular Function: calcium channel inhibitor activity; calcium oxalate binding; heme binding; IgA binding; protein binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity

Biological Process: cell adhesion; female pregnancy; heme catabolic process; negative regulation of immune response; negative regulation of JNK cascade; protein catabolic process; protein-chromophore linkage; receptor-mediated endocytosis; viral reproduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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