NP_001625
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33.4 kDa (292aa) confirmed by MALDI-TOF
NCBI Official Full Name
S-adenosylmethionine decarboxylase proenzyme isoform 1
NCBI Official Synonym Full Names
adenosylmethionine decarboxylase 1
NCBI Protein Information
S-adenosylmethionine decarboxylase proenzyme
UniProt Protein Name
S-adenosylmethionine decarboxylase proenzyme
UniProt Synonym Gene Names
NCBI Summary for AMD1
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]
UniProt Comments for AMD1
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Product References and Citations for AMD1 recombinant protein
Tolbert W.D., et al. (2001) Biochemistry. 40:9484-9494; Xiong H., et al. (1999) J. Biol. Chem. 274:35059-35066
Research Articles on AMD1
Precautions
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Disclaimer
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Products associated with AMD1 recombinant protein
Pathways associated with AMD1 recombinant protein
Diseases associated with AMD1 recombinant protein
Organs/Tissues associated with AMD1 recombinant protein
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