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ANGPTL3 peptide

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Catalog # MBS426847
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
ANGPTL3 peptide
Product Name

ANGPTL3, Peptide

Popular Item
Full Product Name

ANGPTL3 Immunizing Peptide

Product Synonym Names
ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin 5
Product Gene Name
Antibody/Peptide Pairs
ANGPTL3 peptide (MBS426847) is used for blocking the activity of ANGPTL3 antibody (MBS421714)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-EDQYKQLN QQHSQ
OMIM
604774
Form/Format
100 ug of Lyophilized peptide , formulation 5pmol/uL in 5% (v/v) acetonitrile/H20.
Reconstitution
Reconstitute pellet in distilled water where required. For blocking studies, reconstitute pellet in 200 uL distilled water to obtain a 0.5 mg/mL peptide solution.
Preparation and Storage
Shipped at ambient temperature, store at -20°C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ANGPTL3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ANGPTL3 peptide
The peptide eas used in the production of MBS426847 - Goat Anti-ANGPTL3 Antibody. It is currently untested in blocking applications.
NCBI/Uniprot data below describe general gene information for ANGPTL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
angiopoietin-related protein 3 preproprotein
NCBI Official Synonym Full Names
angiopoietin like 3
NCBI Official Symbol
ANGPTL3  [Similar Products]
NCBI Official Synonym Symbols
ANL3; ANG-5; FHBL2; ANGPT5
  [Similar Products]
NCBI Protein Information
angiopoietin-related protein 3
UniProt Protein Name
Angiopoietin-related protein 3
UniProt Synonym Protein Names
Angiopoietin-5; ANG-5
UniProt Gene Name
ANGPTL3  [Similar Products]
UniProt Synonym Gene Names
ANGPT5; ANG-5  [Similar Products]
UniProt Entry Name
ANGL3_HUMAN
NCBI Summary for ANGPTL3
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]
UniProt Comments for ANGPTL3
ANGPTL3: Defects in ANGPTL3 are the cause of familial hypobetalipoproteinemia type 2 (FHBL2); also called combined hypobetalipoproteinemia familial. FHBL2 is a disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption. Affected individuals present with combined hypolipidemia, consisting of extremely low plasma levels of LDL cholesterol, HDL cholesterol, and triglycerides.

Protein type: Inhibitor; Cell adhesion; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cell surface; early endosome; extracellular space; Golgi apparatus; lamellipodium

Molecular Function: enzyme inhibitor activity; growth factor activity; heparin binding; integrin binding; phospholipase inhibitor activity

Biological Process: acylglycerol homeostasis; angiogenesis; artery morphogenesis; cell-matrix adhesion; cholesterol homeostasis; cholesterol metabolic process; fatty acid metabolic process; glycerol metabolic process; integrin-mediated signaling pathway; lipid homeostasis; negative regulation of lipoprotein lipase activity; phospholipid catabolic process; phospholipid homeostasis; phospholipid metabolic process; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of lipid catabolic process; response to hormone stimulus; sequestering of lipid; signal transduction

Disease: Hypobetalipoproteinemia, Familial, 2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with ANGPTL3 peptide
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