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ANGPTL4 recombinant protein :: Angiopoietin-related protein 4 (ANGPTL4) Recombinant Protein

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Catalog # MBS1470528
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $800 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $890 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,070 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,120 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,200 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,360 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,360 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,615 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,785 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,100 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,160 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,205 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,250 +4 FREE 8GB USB
ANGPTL4 recombinant protein
Product Name

Angiopoietin-related protein 4 (ANGPTL4), Recombinant Protein

Full Product Name

Recombinant Bovine Angiopoietin-related protein 4 (ANGPTL4)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-410aa, Full Length of Mature Protein
Sequence
QGRPEPPETP RFASWDEVNV LAHGLLQLGH GLREHVERTR GQLGELERRL GACGAACKDP EGSAAPPRAQ ANLVNPGGGD ASPETLRSLK TQLEAQNSRI QQLFQKVAQQ QRHLEKQQLR IQNLQSQMDH LAPRHLGHEM AKPARRKRLP KMAQLAGPAH NISRLHRLPR DCQELFEEGE RESGLFQIQP QGSPPFLVNC KMTSDGGWTV IQRRQDGSVD FNQPWEAYKD GFGDPQGEFW LGLEKVHHIL GDRGSRLAVQ LQDWEGNAES LQFPIHLGGE DTAYSLQLTP PVASKLGATT FSPSGLSLPF STWDQDHDLR GDKNCARSLS GGWWFGTCSH SNLNGQYFHS IPRQRQQRKK GIFWKTWRGR YYPLQATTIL VQPTAAS
3D Structure
ModBase 3D Structure for Q2KJ51
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Bovine
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ANGPTL4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ANGPTL4 recombinant protein
This gene is a member of the angiopoietin
angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
NCBI/Uniprot data below describe general gene information for ANGPTL4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
45,553 Da
NCBI Official Full Name
angiopoietin-related protein 4
NCBI Official Synonym Full Names
angiopoietin like 4
NCBI Official Symbol
ANGPTL4  [Similar Products]
NCBI Protein Information
angiopoietin-related protein 4
UniProt Protein Name
Angiopoietin-related protein 4
UniProt Synonym Protein Names
Angiopoietin-like protein 4
UniProt Gene Name
ANGPTL4  [Similar Products]
UniProt Comments for ANGPTL4
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ANGPTL4 recombinant protein
Pathways associated with ANGPTL4 recombinant protein
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