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Rabbit DcR3 (NT) Antibody

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Catalog # MBS194061
Unit / Price
  0.1 mg  /  $400 +1 FREE 8GB USB
anti-DcR3 (NT) antibody
Product Name

DcR3 (NT), Antibody

Also Known As

Anti-DcR3 (NT) Antibody

Product Synonym Names
Anti-DcR3 (NT); DcR3 (NT)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Rabbit
Specificity
Anti-DcR3 (NT) [Rabbit antibody to peptide corresponding to aa 31-46 of human DcR3 precursor. Recognizes human, mouse, and rat DcR3.]
This antibody recognizes human, mouse, and rat DcR3 (33 kD).
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen
Peptide corresponding to aa 31- 46 of human DcR3 precursor.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Other Notes
Small volumes of anti-DcR3 (NT) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DcR3 (NT) antibody
Apoptosis is induced by certain cytokines including TNF and Fas ligand through their death domain-containing receptors. Several novel members in the TNF receptor family, including DR3, DR4, DR5 and DR6, function as cell death receptors. Two decoy receptors, DcR1 and DcR2, compete with DR4 and DR5 for binding of their ligand, TRAIL. Another decoy receptor, DcR3/TR6 was discovered recently. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane-associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasLand LIGHT-induced apoptosis. DcR3 transcript is expressed in some lung and colon carcinomas and in some normal tissues.
Product Categories/Family for anti-DcR3 (NT) antibody
Applications Tested/Suitable for anti-DcR3 (NT) antibody
Immunoblot
Application Notes for anti-DcR3 (NT) antibody
Immunoblotting: use at 1:500-1:1,000 dilution.
Positive control: Human heart tissue lysate.
NCBI/Uniprot data below describe general gene information for DcR3 (NT). It may not necessarily be applicable to this product.
NCBI GI #
NCBI Official Full Name
decoy receptor 3 variant 2
NCBI Summary for DcR3 (NT)
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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