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Rabbit FLIP (CT) Antibody

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Catalog # MBS194089
Unit / Price
  0.1 mg  /  $400 +1 FREE 8GB USB
anti-FLIP (CT) antibody
Product Name

FLIP (CT), Antibody

Also Known As

Anti-FLIP gamma / delta (CT) Antibody

Product Synonym Names
Anti-FLIP (CT); FLIP g/d (CT)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Rabbit
Specificity
Anti-FLIP (CT) [Rabbit antibody to peptide corresponding to aa 191-209 at C-terminus of human FLIP. Does not recongnize FLIPa or FLIPb.]
This antibody recognizes human and mouse FLIP gamma (35 kD) and FLIP delta (25 kD) but not FLIP alpha or FLIP beta .
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen
Peptide corresponding to aa 191- 209 at the C-terminus of human FLIP delta /FLIPS form.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Other Notes
Small volumes of anti-FLIP (CT) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FLIP (CT) antibody
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the ICE/CED-3 protease family. Caspase-8 (FLICE) and -10 (FLICE2) are two pivotal members of the ICE/CED-3 protease family. FLICE-inhibitory proteins have been identified in viruses and human cells and are designated v-FLIPs and FLIP, respectively. Human FLIP was cloned by several independent laboratories and designated Casper, I-FLICE, FLAME-1, CASH, and CLARP. FLIP contains two death effector domains and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10 and potently inhibits apoptosis induced by death receptors CD95, DR3, TRAIL-R, and TNFR1. Four splice variants of FLIP have been identified and designated FLIP alpha , beta , gamma , and delta .
Product Categories/Family for anti-FLIP (CT) antibody
Applications Tested/Suitable for anti-FLIP (CT) antibody
Immunoblot
Application Notes for anti-FLIP (CT) antibody
Immunoblotting : use a 1:1,000 dilution.
Positive control: Whole cell lysate from HeLa cells, Jurkat cells, THP-1 cells, A431 cells, K562 cells, or NIH3T3 cells.
NCBI/Uniprot data below describe general gene information for FLIP (CT). It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
NCBI Official Full Name
FLIP
UniProt Comments for FLIP (CT)
Plays a role in the flagellum-specific transport system.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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