View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rabbit IRAK2 Antibody Catalog # MBS194111 Unit / Price 0.1 mg / $520 +1 FREE 8GB USB 5x0.1 mg / $2,190 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name IRAK2, Antibody Full Product Name Anti-IRAK2 Antibody Product Synonym Names Anti-IRAK2; IRAK2 (CT) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Host Rabbit Specificity Anti-IRAK2 [Rabbit antibody to peptide corresponding to aa 546-564 of human IRAK2.]This antibody recognizes full-length human IRAK2 (65 kD). Form/Format 100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography. Antigen Peptide corresponding to aa 546- 564 of human IRAK2. Stabilizer None Preservatives 0.02% sodium azide. Dilutions Instructions Dilute in PBS or medium which is identical to that used in the assay system. Preparation and Storage This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles. Other Notes Small volumes of anti-IRAK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-IRAK2 antibody The pro-inflammatory cytokine IL-1 induces cellular responses through two subunits of its receptor, IL-1 receptor 1 (IL-1R1) and IL- 1 receptor accessory protein (IL-1RacP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF- kappa B, a key transcription factor that mediates inflammatory and immune respones. A novel member of the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 associate with the subunits of the IL-1R complex after IL-1 binding and lead to NF- kappa B activation. IRAKs also associate with Toll-like receptor (TLR) and the dominant negative mutants of IRAKs inhibit LPS-induced NF- kappa B activation. Members of the IRAK/Pelle family play a central role in IL-1R and TLRmediated inflammatory responses. IRAK2 is expressed in a variety of human tissues. Product Categories/Family for anti-IRAK2 antibody Neuroscience and Signal Transduction Antibodies Applications Tested/Suitable for anti-IRAK2 antibody Immunoblot Application Notes for anti-IRAK2 antibody Immunoblotting: use at 1:500-1:1,000 dilution.Positive control: Whole cell lysate from HeLa cells or K562 cells. No crossreactivity with IRAK. TOP Protein Family Interleukin-1 receptor-associated kinase Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP