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AOAH recombinant protein :: Acyloxyacyl hydrolase (AOAH) Recombinant Protein

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Catalog # MBS958374
Unit / Price
  0.05 mg (E-Coli)  /  $965 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,160 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,295 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,400 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,410 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,425 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,470 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,580 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $2,030 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,105 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,125 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,405 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,765 +3 FREE 8GB USB
AOAH recombinant protein
Product Name

Acyloxyacyl hydrolase (AOAH), Recombinant Protein

Popular Item
Also Known As

Recombinant Human Acyloxyacyl hydrolase (AOAH)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
35-575aa, Full Length of Mature Protein
Sequence Length
543
Sequence
LSNGHTCVGC VLVVSVIEQL AQVHNSTVQA SMERLCSYLP EKLFLKTTCY LVIDKFGSDI IKLLSADMNA DVVCHTLEFC KQNTGQPLCH LYPLPKETWK FTLQKARQIV KKSPILKYSR SGSDICSLPV LAKICQKIKL AMEQSVPFKD VDSDKYSVFP TLRGYHWRGR DCNDSDESVY PGRRPNNWDV HQDSNCNGIW GVDPKDGVPY EKKFCEGSQP RGIILLGDSA GAHFHISPEW ITASQMSLNS FINLPTALTN ELDWPQLSGA TGFLDSTVGI KEKSIYLRLW KRNHCNHRDY QNISRNGASS RNLKKFIESL SRNKVLDYPA IVIYAMIGND VCSGKSDPVP AMTTPEKLYS NVMQTLKHLN SHLPNGSHVI LYGLPDGTFL WDNLHNRYHP LGQLNKDMTY AQLYSFLNCL QVSPCHGWMS SNKTLRTLTS ERAEQLSNTL KKIAASEKFT NFNLFYMDFA FHEIIQEWQK RGGQPWQLIE PVDGFHPNEV ALLLLADHFW KKVQLQWPQI LGKENPFNPQ IKQVFGDQGG H
OMIM
102593
3D Structure
ModBase 3D Structure for P28039
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of AOAH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AOAH recombinant protein
Acyloxyacyl hydrolase (AOAH) is a 2-subunit lipase which selectively hydrolyzes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial endotoxins. AOAH may modulate host inflammatory responses to gram-negative bacterial invasion. The 2 subunits are encoded by a single mRNA.
NCBI/Uniprot data below describe general gene information for AOAH. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
61,647 Da
NCBI Official Full Name
acyloxyacyl hydrolase isoform 2 preproprotein
NCBI Official Synonym Full Names
acyloxyacyl hydrolase
NCBI Official Symbol
NCBI Protein Information
acyloxyacyl hydrolase
UniProt Protein Name
Acyloxyacyl hydrolase
Protein Family
UniProt Gene Name
NCBI Summary for AOAH
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
UniProt Comments for AOAH
Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (PubMed:1883828, PubMed:8089145). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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