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AOC1 blocking peptide :: ABP1 Blocking Peptide

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Catalog # MBS9220313
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
AOC1 blocking peptide
Product Name

ABP1 (AOC1), Blocking Peptide

Also Known As

ABP1 Antibody (N-term) Blocking peptide

Product Synonym Names
Amiloride-sensitive amine oxidase [copper-containing]; DAO; Diamine oxidase; Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase; KAO; AOC1; ABP1; DAO1
Product Synonym Gene Name
ABP1; DAO1[Similar Products]
Antibody/Peptide Pairs
ABP1 peptide (MBS9220313) is used for blocking the activity of ABP1 antibody (MBS9201293)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
751
OMIM
104610
3D Structure
ModBase 3D Structure for P19801
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of ABP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Secreted, extracellular space.
Tissue Location
Placenta and kidney.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of AOC1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AOC1 blocking peptide
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
NCBI/Uniprot data below describe general gene information for AOC1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
87,239 Da
NCBI Official Full Name
Amiloride-sensitive amine oxidase
NCBI Official Synonym Full Names
amine oxidase, copper containing 1
NCBI Official Symbol
NCBI Official Synonym Symbols
ABP; DAO; KAO; ABP1; DAO1
  [Similar Products]
NCBI Protein Information
amiloride-sensitive amine oxidase [copper-containing]
UniProt Protein Name
Amiloride-sensitive amine oxidase [copper-containing]
UniProt Synonym Protein Names
Amiloride-binding protein 1; Amine oxidase copper domain-containing protein 1; Histaminase; Kidney amine oxidase; KAO
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
ABP1; DAO1; DAO; Diamine oxidase; KAO  [Similar Products]
UniProt Entry Name
AOC1_HUMAN
NCBI Summary for AOC1
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
UniProt Comments for AOC1
ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - histidine; Amino Acid Metabolism - tryptophan; EC 1.4.3.22; Oxidoreductase; Secreted, signal peptide; Secreted; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: extracellular space; plasma membrane; tight junction

Molecular Function: amine oxidase activity; calcium ion binding; copper ion binding; drug binding; heparin binding; protein complex binding; protein homodimerization activity; quinone binding; receptor activity; zinc ion binding

Biological Process: response to antibiotic; response to drug; xenobiotic metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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