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AP1G2 blocking peptide

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Catalog # MBS9220211
Unit / Price
  0.1 mg  /  $155 +1 FREE 8GB USB
AP1G2 blocking peptide
Product Name

AP1G2, Blocking Peptide

Full Product Name

AP1G2 Antibody (N-term) Blocking peptide

Product Synonym Names
AP-1 complex subunit gamma-like 2; Gamma2-adaptin; G2ad; AP1G2
Antibody/Peptide Pairs
AP1G2 peptide (MBS9220211) is used for blocking the activity of AP1G2 antibody (MBS9214909)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
603534
3D Structure
ModBase 3D Structure for O75843
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of AP1G2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein Note: Mainly localized to perinuclear vesicular structures Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments. Colocalizes with HBV major surface antigen L to cis-Golgi-like structures
Tissue Location
Expressed in all but one (skeletal muscle) tissues examined
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of AP1G2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
AP1G2 blocking peptide
May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV).
NCBI/Uniprot data below describe general gene information for AP1G2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
87,117 Da
NCBI Official Full Name
AP-1 complex subunit gamma-like 2
NCBI Official Synonym Full Names
adaptor related protein complex 1 gamma 2 subunit
NCBI Official Symbol
AP1G2  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
AP-1 complex subunit gamma-like 2
UniProt Protein Name
AP-1 complex subunit gamma-like 2
UniProt Synonym Protein Names
Gamma2-adaptin; G2ad
Protein Family
UniProt Gene Name
AP1G2  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
AP1G2_HUMAN
NCBI Summary for AP1G2
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
UniProt Comments for AP1G2
AP1G2: May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV). Belongs to the adaptor complexes large subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: AP-1 adaptor complex; Golgi apparatus; Golgi membrane; Golgi-associated vesicle; membrane; transport vesicle

Molecular Function: protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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