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APOC1 antigen :: Apolipoprotein CI Antigen

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Catalog # MBS568871
Unit / Price
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  0.2 mg  /  $495 +1 FREE 8GB USB
APOC1 antigen
Product Name

Apolipoprotein CI (APOC1), Antigen

Full Product Name

Apolipoprotein CI Antigen >95%

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
107710
Host
Human Plasma
Purity/Purification
>=95% by SDS-PAGE
Form/Format
Lyophilized from 10 mM Ammonia Bicarbonate, pH 7.4
Preparation and Storage
Store at <=-20 degree C
Other Notes
Small volumes of APOC1 antigen vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for APOC1 antigen
Applications Tested/Suitable for APOC1 antigen
Immunogen Grade
NCBI/Uniprot data below describe general gene information for APOC1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
apolipoprotein C-I
NCBI Official Synonym Full Names
apolipoprotein C1
NCBI Official Symbol
APOC1  [Similar Products]
NCBI Official Synonym Symbols
Apo-CI; ApoC-I; apo-CIB; apoC-IB
  [Similar Products]
NCBI Protein Information
apolipoprotein C-I
UniProt Protein Name
Apolipoprotein C-I
UniProt Synonym Protein Names
Apolipoprotein C1
Protein Family
UniProt Gene Name
APOC1  [Similar Products]
UniProt Synonym Gene Names
Apo-CI; ApoC-I  [Similar Products]
UniProt Entry Name
APOC1_HUMAN
NCBI Summary for APOC1
This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. [provided by RefSeq, Mar 2016]
UniProt Comments for APOC1
APOC1: Appears to modulate the interaction of APOE with beta- migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification. Belongs to the apolipoprotein C1 family.

Protein type: Inhibitor; Lipid-binding; Secreted, signal peptide; Endoplasmic reticulum; Secreted

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: chylomicron; endoplasmic reticulum

Molecular Function: fatty acid binding; lipase inhibitor activity; phosphatidylcholine binding; phospholipase inhibitor activity

Biological Process: cholesterol efflux; cholesterol metabolic process; lipid metabolic process; lipoprotein metabolic process; negative regulation of cholesterol transport; negative regulation of fatty acid biosynthetic process; negative regulation of lipid catabolic process; negative regulation of lipid metabolic process; negative regulation of lipoprotein lipase activity; negative regulation of receptor-mediated endocytosis; phospholipid efflux; positive regulation of catalytic activity; regulation of cholesterol transport; triacylglycerol metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with APOC1 antigen
 Products by Pathway  Pathway Diagram
 Statin Pathway antibodies  Statin Pathway Diagram
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