• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

APOC2 antigen :: Apolipoprotein CII Antigen

Scan QR to view Datasheet
Catalog # MBS568608
Unit / Price
  0.1 mg  /  $385 +1 FREE 8GB USB
APOC2 antigen
Product Name

Apolipoprotein CII (APOC2), Antigen

Full Product Name

Apolipoprotein CII Antigen >95%

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
207750
Host
Human Plasma
Purity/Purification
>=95% by SDS-PAGE
Form/Format
Lyophilized from 10 mM Ammonia Bicarbonate, pH 7.4
Preparation and Storage
Store at <=-20 degree C
Other Notes
Small volumes of APOC2 antigen vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for APOC2 antigen
Applications Tested/Suitable for APOC2 antigen
Immunogen Grade
NCBI/Uniprot data below describe general gene information for APOC2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,284 Da[Similar Products]
NCBI Official Full Name
apolipoprotein C-II
NCBI Official Synonym Full Names
apolipoprotein C2
NCBI Official Symbol
APOC2  [Similar Products]
NCBI Official Synonym Symbols
APO-CII; APOC-II
  [Similar Products]
NCBI Protein Information
apolipoprotein C-II
UniProt Protein Name
Apolipoprotein C-II
UniProt Synonym Protein Names
Apolipoprotein C2
Protein Family
UniProt Gene Name
APOC2  [Similar Products]
UniProt Synonym Gene Names
APC2; Apo-CII; ApoC-II; ProapoC-II  [Similar Products]
UniProt Entry Name
APOC2_HUMAN
NCBI Summary for APOC2
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
UniProt Comments for APOC2
APOC2: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B). It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Belongs to the apolipoprotein C2 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: chylomicron; early endosome; extracellular region; extracellular space

Molecular Function: lipase inhibitor activity; lipid binding; phospholipase activator activity; phospholipase binding; protein homodimerization activity

Biological Process: cholesterol efflux; cholesterol homeostasis; lipid catabolic process; lipoprotein metabolic process; negative regulation of catalytic activity; negative regulation of cholesterol transport; negative regulation of lipid metabolic process; negative regulation of receptor-mediated endocytosis; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity; retinoid metabolic process; reverse cholesterol transport

Disease: Apolipoprotein C-ii Deficiency
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000