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Apoc3 recombinant protein :: Apolipoprotein C-III (Apoc3) Recombinant Protein

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Catalog # MBS962400
Unit / Price
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  0.01 mg (E-Coli)  /  $200 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $260 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $430 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $645 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $685 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $865 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $875 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $985 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,100 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,240 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,540 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,630 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,805 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,545 +3 FREE 8GB USB
SDS-Page
Product Name

Apolipoprotein C-III (Apoc3), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse Apolipoprotein C-III (Apoc3)

Product Synonym Names
Apolipoprotein C3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS962400 COA
Sequence Positions
21-99. Full Length of Mature Protein
Sequence
EEVEGSLLLG SVQGYMEQAS KTVQDALSSV QESDIAVVAR GWMDNHFRFL KGYWSKFTDK FTGFWDSNPE DQPTPAIES
3D Structure
ModBase 3D Structure for P33622
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Production Note
Special Offer: The E. coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E. coli host-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E. coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E. coli host-expressed protein for the fastest delivery among all hosts. Please contact us or email to support@mybiosource.com for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Apoc3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Apoc3 recombinant protein
Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.

Apoc3 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Apoc3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24.8kD
NCBI Official Full Name
apolipoprotein C-III isoform b
NCBI Official Synonym Full Names
apolipoprotein C-III
NCBI Official Symbol
Apoc3  [Similar Products]
NCBI Official Synonym Symbols
apo-CIII; apoC-III
  [Similar Products]
NCBI Protein Information
apolipoprotein C-III
UniProt Protein Name
Apolipoprotein C-III
UniProt Synonym Protein Names
Apolipoprotein C3
Protein Family
UniProt Gene Name
Apoc3  [Similar Products]
UniProt Synonym Gene Names
Apo-CIII; ApoC-III  [Similar Products]
UniProt Entry Name
APOC3_MOUSE
NCBI Summary for Apoc3
This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL). The encoded protein is thought to regulate the metabolism of triglyceride-rich lipoproteins and play a role in lipid storage and the mobilization of fat cells. This gene is clustered with three other apolipoprotein genes on chromosome 9 and is associated with coronary disease. Mice lacking this gene have lower levels of total cholesterol in the plasma. Mutations in the human genes causes hyperalphalipoproteinemia 2, a disorder of lipid metabolism which results in a favorable lipid profile (lower LDL-cholesterol, higher HDL-cholesterol and lower levels of serum triglycerides when fasting and after a meal). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
UniProt Comments for Apoc3
APOC3: Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles. Defects in APOC3 are the cause of hyperalphalipoproteinemia type 2 (HALP2). HALP2 is a condition characterized by high levels of high density lipoprotein (HDL) and increased HDL cholesterol levels. Belongs to the apolipoprotein C3 family.

Protein type: Secreted; Secreted, signal peptide; Lipid-binding

Cellular Component: cell; chylomicron; extracellular region; extracellular space

Molecular Function: lipase inhibitor activity; lipid binding; phospholipid binding

Biological Process: cholesterol homeostasis; cholesterol metabolic process; lipid catabolic process; lipid metabolic process; lipid transport; lipoprotein metabolic process; lipoprotein transport; negative regulation of lipoprotein lipase activity; response to peptide hormone stimulus; transport; triacylglycerol catabolic process; triacylglycerol metabolic process; triacylglycerol mobilization
Product References and Citations for Apoc3 recombinant protein
Characterization of the mouse apolipoprotein Apoa-1/Apoc-3 gene locus genomic, mRNA, and protein sequences with comparisons to other species.Januzzi J.L., Azrolan N., O'Connell A., Aalto-Setala K., Breslow J.L.Genomics 14:1081-1088(1992) Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.Puppione D.L., Yam L.M., Bassilian S., Souda P., Castellani L.W., Schumaker V.N., Whitelegge J.P.Biochim. Biophys. Acta 1764:1363-1371(2006)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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