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ARFGAP1 recombinant protein :: ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) Recombinant Protein

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Catalog # MBS1301288
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $820 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $905 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,100 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,135 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,210 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,220 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,375 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,385 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,640 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,830 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,130 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,200 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,230 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,295 +4 FREE 8GB USB
ARFGAP1 recombinant protein
Product Name

ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1), Recombinant Protein

Full Product Name

Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-406aa, full length protein
Sequence
MASPRTRKVL KEVRVQDENN VCFECGAFNP QWVSVTYGIW ICLECSGRHR GLGVHLSFVR SVTMDKWKDI ELEKMKAGGN AKFREFLESQ EDYDPCWSLQ EKYNSRAAAL FRDKVVALAE GREWSLESSP AQNWTPPQPR TLPSMVHRVS GQPQSVTASS DKAFEDWLND DLGSYQGAQG NRYVGFGNTP PPQKKEDDFL NNAMSSLYSG WSSFTTGASR FASAAKEGAT KFGSQASQKA SELGHSLNEN VLKPAQEKVK EGKIFDDVSS GVSQLASKVQ GVGSKGWRDV TTFFSGKAEG PLDSPSEGHS YQNSGLDHFQ NSNIDQSFWE TFGSAEPTKT RKSPSSDSWT CADTSTERRS SDSWEVWGSA STNRNSNSDG GEGGEGTKKA VPPAVPTDDG WDNQNW
OMIM
608377
3D Structure
ModBase 3D Structure for Q8N6T3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ARFGAP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ARFGAP1 recombinant protein
This protein is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
NCBI/Uniprot data below describe general gene information for ARFGAP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,705 Da
NCBI Official Full Name
ADP-ribosylation factor GTPase-activating protein 1 isoform c
NCBI Official Synonym Full Names
ADP ribosylation factor GTPase activating protein 1
NCBI Official Symbol
ARFGAP1  [Similar Products]
NCBI Official Synonym Symbols
ARF1GAP; HRIHFB2281
  [Similar Products]
NCBI Protein Information
ADP-ribosylation factor GTPase-activating protein 1
UniProt Protein Name
ADP-ribosylation factor GTPase-activating protein 1
UniProt Synonym Protein Names
ADP-ribosylation factor 1 GTPase-activating protein; ARF1 GAP; ARF1-directed GTPase-activating protein
UniProt Gene Name
ARFGAP1  [Similar Products]
UniProt Synonym Gene Names
ARF1GAP; ARF GAP 1; ARF1 GAP  [Similar Products]
NCBI Summary for ARFGAP1
The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UniProt Comments for ARFGAP1
GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ARFGAP1 recombinant protein
 Reference Product  PubMed Publications
 ARF1 recombinant protein  >32 publications with ARFGAP1 and ARF1
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