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ARHGAP29 cdna clone

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Catalog # MBS1274934
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ARHGAP29 cdna clone
Product Name

ARHGAP29, cDNA Clone

Popular Item
Full Product Name

ARHGAP29 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgattgctc acaaacagaa aaagacaaag aaaaaacgtg cttgggcatc aggtcaactc tctactgata ttacaacttc tgaaatgggg ctcaagtcct taagttccaa ctctattttt gatccggatt acatcaagga gttggtgaat gatatcagga agttctccca catgttacta tatttgaaag aagccatatt ttcagactgt tttaaagaag ttattcatat acgtctagag gaactgctcc gtgttttaaa gtctataatg aataaacatc agaacctcaa ttctgttgat cttcaaaatg ctgcagaaat gctcactgca aaagtgaaag ctgtgaactt cacagaagtt aatgaagaaa acaaaaacga tctcttccag gaagtgtttt cttctattga aactttggca tttacctttg gaaatatcct tacaaacttc cttatgggag atgtaggcaa tgattcatta ttgcgactgc ctgtttctcg agaaactaag tcgtttgaaa atgtttctgt ggaatcagtg gactcatcca gtgaaaaagg aaatttttcc cctttagaac tagacaacgt gctgttaaag aacactgact ctatcgagct ggctttgtca tatgctaaaa cttggtcaaa atatactaag aacatagttt catgggttga aaaaaagctt aacttggaat tggagtccac tagaaatatg gtcaagttgg cagaggcaac tagaactaac attggaattc aggagttcat gccactgcag tctctgttta ctaatgctct tcttaatgat atagaaagca gtcacctttt acaacaaaca attgcagctc tccaggctaa caaatttgtg cagcctctac ttggaaggaa aaatgaaatg gaaaaacaaa ggaaagaaat aaaagagctt tggaaacagg agcaaaataa aatgcttgaa gcagagaatg ctctcaaaaa ggcaaaatta ttatgcatgc aacgtcaaga tgaatatgag aaagcaaagt cttccatgtt tcgtgcagaa gaggagcatc tgtcttcaag tggcggatta gcaaaaaatc tcaacaagca actagaaaaa aagcgaaggt tggaagagga ggctctccaa aaagtaacga tctttttctt ttttatttgc aagttgaatt ag
OMIM
610496
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ARHGAP29 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ARHGAP29. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,194 Da
NCBI Official Full Name
Homo sapiens Rho GTPase activating protein 29, mRNA
NCBI Official Synonym Full Names
Rho GTPase activating protein 29
NCBI Official Symbol
ARHGAP29  [Similar Products]
NCBI Official Synonym Symbols
PARG1
  [Similar Products]
NCBI Protein Information
rho GTPase-activating protein 29
UniProt Protein Name
Rho GTPase-activating protein 29
UniProt Synonym Protein Names
PTPL1-associated RhoGAP protein 1; Rho-type GTPase-activating protein 29
UniProt Gene Name
ARHGAP29  [Similar Products]
UniProt Synonym Gene Names
PARG1  [Similar Products]
UniProt Entry Name
RHG29_HUMAN
NCBI Summary for ARHGAP29
Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]
UniProt Comments for ARHGAP29
ARHGAP29: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activator activity; PDZ domain binding

Biological Process: regulation of small GTPase mediated signal transduction; Rho protein signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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