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ARL2BP recombinant protein :: ADP-ribosylation factor-like protein 2-binding protein Recombinant Protein

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Catalog # MBS717212
Unit / Price
  0.01 mg  /  $110 +1 FREE 8GB USB
  0.05 mg  /  $175 +1 FREE 8GB USB
  0.1 mg  /  $220 +1 FREE 8GB USB
  0.2 mg  /  $295 +1 FREE 8GB USB
  0.5 mg  /  $580 +1 FREE 8GB USB
  1 mg  /  $855 +1 FREE 8GB USB
SDS-PAGE
Product Name

ADP-ribosylation factor-like protein 2-binding protein (ARL2BP), Recombinant Protein

Also Known As

Recombinant Human ADP-ribosylation factor-like protein 2-binding protein

Product Synonym Names
Binder of ARF2 protein 1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-163aa; Full Length
Sequence Length
163
Sequence
MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH
OMIM
615407
3D Structure
ModBase 3D Structure for Q9Y2Y0
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ARL2BP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ARL2BP recombinant protein
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Product Categories/Family for ARL2BP recombinant protein

ARL2BP recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for ARL2BP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46.2kD
NCBI Official Full Name
ADP-ribosylation factor-like protein 2-binding protein
NCBI Official Synonym Full Names
ADP ribosylation factor like GTPase 2 binding protein
NCBI Official Symbol
ARL2BP  [Similar Products]
NCBI Official Synonym Symbols
BART; RP66; BART1
  [Similar Products]
NCBI Protein Information
ADP-ribosylation factor-like protein 2-binding protein
UniProt Protein Name
ADP-ribosylation factor-like protein 2-binding protein
UniProt Synonym Protein Names
Binder of ARF2 protein 1
UniProt Gene Name
ARL2BP  [Similar Products]
UniProt Synonym Gene Names
BART; BART1; ARF-like 2-binding protein; ARL2-binding protein  [Similar Products]
UniProt Entry Name
AR2BP_HUMAN
NCBI Summary for ARL2BP
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
UniProt Comments for ARL2BP
ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: centrosome; cilium; cytosol; midbody; mitochondrial intermembrane space; mitochondrial matrix; nucleus; spindle

Molecular Function: GTPase regulator activity; protein binding; transcription coactivator activity

Biological Process: energy reserve metabolic process; maintenance of protein localization in nucleus; positive regulation of tyrosine phosphorylation of Stat3 protein; regulation of catalytic activity; regulation of insulin secretion; signal transduction

Disease: Retinitis Pigmentosa With Or Without Situs Inversus
Product References and Citations for ARL2BP recombinant protein
The ARF-like 2 (ARL2) -binding protein, BART. Purification, cloning, and initial characterization.Sharer J.D., Kahn R.A.J. Biol. Chem. 274:27553-27561(1999) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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