NP_620689.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Related Accession #
Molecular Weight
58,160 Da
NCBI Official Full Name
homeobox protein ARX
NCBI Official Synonym Full Names
aristaless related homeobox
NCBI Official Synonym Symbols
ISSX; PRTS; CT121; EIEE1; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1 [Similar Products]
NCBI Protein Information
homeobox protein ARX
UniProt Protein Name
Homeobox protein ARX
UniProt Synonym Protein Names
Aristaless-related homeobox
NCBI Summary for ARX
This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Expansion of a polyalanine tract and other mutations in this gene cause X-linked cognitive disability and epilepsy. [provided by RefSeq, Jul 2016]
UniProt Comments for ARX
Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with ARX blocking peptide
Pathways associated with ARX blocking peptide
Diseases associated with ARX blocking peptide
Disease Name |
Pubmed Publications |
Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related Antibodies |
>91 publications with ARX and Mental Retardation, X-Linked, With Or Without Seizures, Arx-Related |
Diabetes Mellitus Antibodies |
>29 publications with ARX and Diabetes Mellitus |
Disease Models, Animal Antibodies |
>29 publications with ARX and Disease Models, Animal |
Abnormalities, Multiple Antibodies |
>28 publications with ARX and Abnormalities, Multiple |
Lissencephaly, X-Linked, 2 Antibodies |
>8 publications with ARX and Lissencephaly, X-Linked, 2 |
Learning Disorders Antibodies |
>7 publications with ARX and Learning Disorders |
Hyperplasia Antibodies |
>6 publications with ARX and Hyperplasia |
Fibrosis Antibodies |
>6 publications with ARX and Fibrosis |
Kidney Diseases Antibodies |
>4 publications with ARX and Kidney Diseases |
Epileptic Encephalopathy, Early Infantile, 1 Antibodies |
>4 publications with ARX and Epileptic Encephalopathy, Early Infantile, 1 |
Organs/Tissues associated with ARX blocking peptide
|