NP_569059.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,996 Da
NCBI Official Full Name
ankyrin repeat and SOCS box protein 12
NCBI Official Synonym Full Names
ankyrin repeat and SOCS box containing 12
NCBI Protein Information
ankyrin repeat and SOCS box protein 12; ankyrin repeat and SOCS box-containing 12; ankyrin repeat domain-containing SOCS box protein Asb-12
UniProt Protein Name
Ankyrin repeat and SOCS box protein 12
UniProt Synonym Gene Names
UniProt Entry Name
ASB12_HUMAN
NCBI Summary for ASB12
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jan 2011]
UniProt Comments for ASB12
ASB12: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Chromosomal Location of Human Ortholog: Xq11.2
Biological Process: protein ubiquitination
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Pathways associated with ASB12 elisa kit
Diseases associated with ASB12 elisa kit
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