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ASGR2 cdna clone

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Catalog # MBS1270193
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ASGR2 cdna clone
Product Name

ASGR2, cDNA Clone

Popular Item
Full Product Name

ASGR2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggccaagg actttcaaga tatccagcag ctgagctcgg aggaaaatga ccatcctttc catcaagggc cacctcctgc ccagcccctg gcacagcgtc tctgctccat ggtctgcttc agtctgcttg ccctgagctt caacatcctg ctgctggtgg tcatctgtgt gactgggtcc caaagtgcac agctgcaagc cgagctgcgg agcctgaagg aagctttcag caacttctcc tcgagcaccc tgacggaggt ccaggcaatc agcacccacg gaggcagcgt gggtgacaag atcacatccc taggagccaa gctggagaaa cagcagcagg acctgaaagc agatcacgat gccctgctct tccatctgaa gcacttcccc gtggacctgc gcttcgtggc ctgccagatg gagctcctcc acagcaacgg ctcccaaagg acctgctgcc ccgtcaactg ggtggagcac caaggcagct gctactggtt ctctcactcc gggaaggcct gggctgaggc ggagaagtac tgccagctgg agaacgcaca cctggtggtc atcaactcct gggaggagca gaaattcatt gtacaacaca cgaacccctt caatacctgg ataggtctca cggacagtga tggctcttgg aaatgggtgg atggcacaga ctataggcac aactacaaga actgggctgt cactcagcca gataattggc acgggcacga gctgggtgga agtgaagact gtgttgaagt ccagccggat ggccgctgga acgatgactt ctgcctgcag gtgtaccgct gggtgtgtga gaaaaggcgg aatgccaccg gcgaggtggc ctga
OMIM
108361
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ASGR2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ASGR2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,550 Da
NCBI Official Full Name
Homo sapiens asialoglycoprotein receptor 2, mRNA
NCBI Official Synonym Full Names
asialoglycoprotein receptor 2
NCBI Official Symbol
ASGR2  [Similar Products]
NCBI Official Synonym Symbols
HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
  [Similar Products]
NCBI Protein Information
asialoglycoprotein receptor 2
UniProt Protein Name
Asialoglycoprotein receptor 2
UniProt Synonym Protein Names
C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
UniProt Gene Name
ASGR2  [Similar Products]
UniProt Synonym Gene Names
CLEC4H2; ASGP-R 2; ASGPR 2; HL-2  [Similar Products]
UniProt Entry Name
ASGR2_HUMAN
NCBI Summary for ASGR2
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
UniProt Comments for ASGR2
ASGP-R: cell surface receptor that mediates the endocytosis of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 17p

Molecular Function: asialoglycoprotein receptor activity; protein binding

Biological Process: cell surface receptor linked signal transduction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with ASGR2 cdna clone
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