• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Asgr2 recombinant protein :: Asialoglycoprotein receptor 2 (Asgr2) Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS7053730
Unit / Price
  0.01 mg (E-Coli)  /  $200 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $260 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $430 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $685 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,125 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
SDS-Page
Product Name

Asialoglycoprotein receptor 2 (Asgr2), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse Asialoglycoprotein receptor 2 (Asgr2), partial

Product Synonym Names
Hepatic lectin 2
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
80-301aa; Extracellular Domain
Sequence
QSIQLQEEFR TLKETFSNFS SSTLMEFGAL DTLGGSTNAI LTSWLAQLEE KQQQLKADHS TLLFHLKHFP MDLRTLTCQL AYFQSNGTEC CPVNWVEFGG SCYWFSRDGL TWAEADQYCQ LENAHLLVIN SREEQDFVVK HRSQFHIWIG LTDRDGSWKW VDGTDYRSNY RNWAFTQPDN WQGHEQGGGE DCAEILSDGH WNDNFCQQVN RWVCEKRRNI TH
3D Structure
ModBase 3D Structure for P24721
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Asgr2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Asgr2 recombinant protein
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Product Categories/Family for Asgr2 recombinant protein

Asgr2 recombinant protein SDS-Page image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Asgr2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
asialoglycoprotein receptor 2 isoform a
NCBI Official Synonym Full Names
asialoglycoprotein receptor 2
NCBI Official Symbol
Asgr2  [Similar Products]
NCBI Official Synonym Symbols
Asgr; HL-2; ASGPR2; Asgr-2
  [Similar Products]
NCBI Protein Information
asialoglycoprotein receptor 2
UniProt Protein Name
Asialoglycoprotein receptor 2
UniProt Synonym Protein Names
Hepatic lectin 2; HL-2; mHL-2
UniProt Gene Name
Asgr2  [Similar Products]
UniProt Synonym Gene Names
Asgr-2; ASGP-R 2; ASGPR 2; HL-2; mHL-2  [Similar Products]
NCBI Summary for Asgr2
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Sep 2015]
UniProt Comments for Asgr2
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Product References and Citations for Asgr2 recombinant protein
"Impaired receptor-mediated endocytosis by the asialoglycoprotein receptor in ethanol-fed mice: implications for studying the role of this receptor in alcoholic apoptosis." Dalton S.R., Wiegert R.L., Baldwin C.R., Kassel K.M., Casey C.A. Biochem. Pharmacol. 65:535-543(2003)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with Asgr2 recombinant protein
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >2 publications with Asgr2 and Hepatitis
Organs/Tissues associated with Asgr2 recombinant protein
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with Asgr2 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000