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ASPA cdna clone

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Catalog # MBS1268608
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
ASPA cdna clone
Product Name

ASPA, cDNA Clone

Popular Item
Full Product Name


Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
atgacttctt gtcacattgc tgaagaacat atacaaaagg ttgctatctt tggaggaacc catgggaatg agctaaccgg agtatttctg gttaagcatt ggctagagaa tggcgctgag attcagagaa cagggctgga ggtaaaacca tttattacta accccagagc agtgaagaag tgtaccagat atattgactg tgacctgaat cgcatttttg accttgaaaa tcttggcaaa aaaatgtcag aagatttgcc atatgaagtg agaagggctc aagaaataaa tcatttattt ggtccaaaag acagtgaaga ttcctatgac attatttttg accttcacaa caccacctct aacatggggt gcactcttat tcttgaggat tccaggaata actttttaat tcagatgttt cattacatta agacttctct ggctccacta ccctgctacg tttatctgat tgagcatcct tccctcaaat atgcgaccac tcgttccata gccaagtatc ctgtgggtat agaagttggt cctcagcctc aaggggttct gagagctgat atcttggatc aaatgagaaa aatgattaaa catgctcttg attttataca tcatttcaat gaaggaaaag aatttcctcc ctgcgccatt gaggtctata aaattataga gaaagttgat tacccccggg atgaaaatgg agaaattgct gctatcatcc atcctaatct gcaggatcaa gactggaaac cactgcatcc tggggatccc atgtttttaa ctcttgatgg gaagacgatc ccactgggcg gagactgtac cgtgtacccc gtgtttgtga atgaggccgc atattacgaa aagaaagaag cttttgcaaa gacaactaaa ctaacgctca atgcaaaaag tattcgctgc tgtttacatt ag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ASPA cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ASPA. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Related Accession #
Molecular Weight
35,735 Da
NCBI Official Full Name
Homo sapiens aspartoacylase (Canavan disease), mRNA
NCBI Official Synonym Full Names
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
UniProt Protein Name
UniProt Synonym Protein Names
Aminoacylase-2; ACY-2
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
ACY2; ASP; ACY-2  [Similar Products]
UniProt Entry Name
NCBI Summary for ASPA
This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ASPA
ASPA: Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids. Defects in ASPA are the cause of Canavan disease (CAND); also known as spongy degeneration of the brain. CAND is a rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average. Belongs to the AspA/AstE family. Aspartoacylase subfamily.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Cell development/differentiation; Hydrolase; EC; Amino Acid Metabolism - histidine

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: cytoplasm; cytosol

Molecular Function: aminoacylase activity; aspartoacylase activity; protein binding

Biological Process: amino acid biosynthetic process; aspartate catabolic process

Disease: Canavan Disease
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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