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ATP6V0A1 cdna clone

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Catalog # MBS1276841
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $470 +1 FREE 8GB USB
ATP6V0A1 cdna clone
Product Name

ATP6V0A1, cDNA Clone

Also Known As

ATP6V0A1 cDNA Clone

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
2514
Sequence
atgggggagc ttttccggag tgaagaaatg acactggccc agctttttct acagtcagag gctgcttatt gttgtgtcag tgaattagga gaacttggaa aggttcagtt tcgtgactta aatccagatg tgaatgtttt ccaacggaaa tttgtgaatg aagttagaag atgtgaagaa atggatcgaa agcttcgatt tgttgagaaa gagataagaa aagctaacat tccgattatg gacaccggtg aaaacccaga ggttcccttc ccccgggaca tgattgactt agaggccaat tttgagaaga ttgaaaatga actgaaggaa atcaacacaa accaggaagc tctgaagaga aacttcctgg aactgaccga attaaaattt atacttcgca aaactcagca attttttgat gagatggcgg atccagactt gttggaagag tcctcatccc tcttggagcc aagtgagatg ggaagaggca ctcctttaag acttggcttc gtggctggtg tcattaaccg ggagcgcatc cctacttttg agcgcatgct ttggcgggta tgccggggaa atgtgttcct gcgacaggct gaaatcgaga accccctgga ggatcctgtg actggcgact acgtgcacaa gtctgtgttt atcattttct tccaaggcga tcagctgaaa aacagagtca agaaaatctg tgaagggttc cgagcctcac tctatccctg tcctgagaca ccacaggaga ggaaggaaat ggcttctgga gtgaatacca ggattgatga tctccaaatg gttctgaatc aaacggagga tcaccgccag agggttctgc aggcagctgc taagaacatc cgtgtctggt tcatcaaagt gcggaagatg aaggccatct atcacaccct gaacctgtgc aacatagatg tgactcagaa atgcttgatt gcagaggtct ggtgccctgt caccgacctt gactccatcc agtttgcact cagaaggggc acggaacaca gtggttccac tgtaccttcc attttgaaca ggatgcagac aaaccagact cccccaacct ataacaaaac caacaagttt acctatggct ttcagaacat agtagatgct tatggaattg gaacttaccg agagataaat ccagctccgt atactattat cacgttccct tttctatttg ctgtgatgtt tggagacttc ggtcatggca ttttaatgac cctttttgct gtgtggatgg tactgaggga gagccggatc ctttcccaga agaatgagaa tgagatgttt agcactgtgt tcagtggtcg atacattatt ttattgatgg gtgtgttctc catgtacact ggcctcatct acaatgattg cttttccaag tctcttaata tctttgggtc atcctggagt gtacggccga tgtttactta taattggact gaagagacgc ttcgggggaa ccctgttcta cagctgaacc cagccctccc tggagtgttt ggtggaccat acccttttgg cattgatcca atttggaaca ttgctaccaa taaactgacg ttcttgaact cctttaagat gaagatgtct gttatccttg gtatcatcca tatgctgttt ggagtcagcc tgagtctgtt caaccatatc tatttcaaga agcccctgaa tatctacttt ggatttattc ctgaaataat cttcatgacc tctttgtttg gctatttggt tatccttatt ttttacaagt ggacggccta tgatgctcat acctctgaga atgcaccaag ccttctgatc catttcataa acatgttcct cttttcctac ccagagtctg gttattcaat gttgtattct ggacagaaag gaattcagtg tttcctggta gtggttgcac tactgtgtgt accttggatg ctgctgttta aaccattggt ccttcgccgt cagtatttga ggagaaagca tttgggaact ctcaactttg gtgggatcag ggtgggcaac ggaccgacag aggaggatgc tgagattatt cagcatgacc agctctccac ccactcagag gacgcagacg agccttccga ggacgaagtg tttgactttg gggacaccat ggtccaccag gccatccaca ccatcgagta ctgcctgggc tgcatctcca acactgcctc ctacttgcgg ctctgggccc tcagcctcgc tcatgcgcag ctgtctgagg tgctttggac catggtgatc cacatcggcc tgagcgtgaa gagcttggcg ggaggtttgg tgctgttctt cttcttcact gcctttgcca ccctgaccgt ggccatcctc ctgatcatgg agggcctctc ggcctttctc cacgcactgc gcttacactg ggttgagttc cagaataaat tctacagcgg gaccggtttc aagttcttac ccttctcctt cgagcatatt cgggaaggga agtttgaaga gtga
OMIM
192130
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of ATP6V0A1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ATP6V0A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
96,600 Da
NCBI Official Full Name
Homo sapiens ATPase, H+ transporting, lysosomal V0 subunit a1, mRNA
NCBI Official Synonym Full Names
ATPase H+ transporting V0 subunit a1
NCBI Official Symbol
ATP6V0A1  [Similar Products]
NCBI Official Synonym Symbols
a1; Stv1; VPP1; Vph1; ATP6N1; ATP6N1A
  [Similar Products]
NCBI Protein Information
V-type proton ATPase 116 kDa subunit a isoform 1
UniProt Protein Name
V-type proton ATPase 116 kDa subunit a isoform 1
UniProt Synonym Protein Names
Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit; Vacuolar adenosine triphosphatase subunit Ac116; Vacuolar proton pump subunit 1; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1
Protein Family
UniProt Gene Name
ATP6V0A1  [Similar Products]
UniProt Synonym Gene Names
ATP6N1; ATP6N1A; VPP1; V-ATPase 116 kDa isoform a1  [Similar Products]
UniProt Entry Name
VPP1_HUMAN
NCBI Summary for ATP6V0A1
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ATP6V0A1
ATP6V0A1: Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle. Belongs to the V-ATPase 116 kDa subunit family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Motility/polarity/chemotaxis; Membrane protein, integral; Transporter, ion channel; Transporter, iron; Membrane protein, multi-pass; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: cell; cytoplasm; endosome membrane; Golgi apparatus; intracellular membrane-bound organelle; nucleoplasm; phagocytic vesicle membrane; plasma membrane; vacuolar proton-transporting V-type ATPase complex

Molecular Function: ATPase binding; hydrogen ion transporting ATPase activity, rotational mechanism; protein binding

Biological Process: ATP synthesis coupled proton transport; insulin receptor signaling pathway; regulation of macroautophagy; transferrin transport; vacuolar acidification
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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