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AURKB elisa kit :: Rat aurora kinase B ELISA Kit

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Catalog # MBS9330024
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AURKB elisa kit
Product Name

aurora kinase B (AURKB), ELISA Kit

Full Product Name

Rat Serine/threonine-protein kinase 12, AURKB ELISA Kit

Product Synonym Names
Rat Serine/threonine-protein kinase 12 (AURKB) ELISA kit; AIK2; AIM-1; AIM1; ARK2; AurB; IPL1; STK12; STK5; aurkb-sv1; aurkb-sv2; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora-1; aurora-B; serine/threonine kinase 12; aurora kinase B
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
3D Structure
ModBase 3D Structure for O55099
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of AURKB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for AURKBpurchase
MBS9330024 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the aurora kinase B (AURKB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AURKB. The ELISA analytical biochemical technique of the MBS9330024 kit is based on AURKB antibody-AURKB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AURKB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AURKB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for AURKB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,234 Da
NCBI Official Full Name
aurora kinase B
NCBI Official Synonym Full Names
aurora kinase B
NCBI Official Symbol
Aurkb  [Similar Products]
NCBI Official Synonym Symbols
Aim1; ARK-2; STK-1; Stk12
  [Similar Products]
NCBI Protein Information
aurora kinase B; AIM-1; aurora 1; aurora-B; aurora-related kinase 2; serine/threonine kinase 12; aurora/IPL1-related kinase 2; serine/threonine-protein kinase 5; serine/threonine-protein kinase 12; serine/threonine-protein kinase aurora-B; aurora- and Ipl1-like midbody-associated protein 1
UniProt Protein Name
Aurora kinase B
UniProt Synonym Protein Names
Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B
Protein Family
UniProt Gene Name
Aurkb  [Similar Products]
UniProt Synonym Gene Names
Aik2; Aim1; Airk2; Ark2; Stk1; Stk12; Stk5; ARK-2; Aurora-related kinase 2  [Similar Products]
UniProt Entry Name
AURKB_RAT
NCBI Summary for AURKB
kinase; involved in proper progression of cytokinesis [RGD, Feb 2006]
UniProt Comments for AURKB
AurB: a member of the AUR family of kinases. May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Expressed during S and G2/M phase and expression is upregulated in cancer cells during M phase. Localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis. Colocalizes with gamma tubulin in the mid-body. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Overexpressed in colorectal and other cancer cell lines and thought to cause aneuploidy via histone phosphorylation.

Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Other group; AUR family

Cellular Component: intercellular bridge; spindle microtubule; cytoplasm; spindle; midbody; spindle midzone; spindle pole centrosome; nucleus; condensed nuclear chromosome, pericentric region; chromocenter

Molecular Function: protein serine/threonine kinase activity; metal ion binding; protein serine/threonine/tyrosine kinase activity; histone serine kinase activity; ATP binding; protein kinase activity

Biological Process: positive regulation of cytokinesis; spindle stabilization; cell proliferation; mitotic spindle organization and biogenesis; spindle midzone assembly involved in mitosis; abscission; negative regulation of transcription from RNA polymerase II promoter; negative regulation of protein binding; regulation of cytokinesis; protein amino acid phosphorylation; negative regulation of cytokinesis; negative regulation of B cell apoptosis; aging
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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