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BAG2 cdna clone

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Catalog # MBS1269691
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
BAG2 cdna clone
Product Name

BAG2, cDNA Clone

Full Product Name

BAG2 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGGCTCAGG CGAAGATCAA CGCTAAAGCC AACGAGGGGC GCTTCTGCCG CTCCTCCTCC ATGGCTGACC GCTCCAGCCG CCTGCTGGAG AGCCTGGACC AGCTGGAGCT CAGGGTTGAA GCTTTGAGAG AAGCAGCAAC TGCTGTTGAG CAAGAGAAAG AAATCCTTCT GGAAATGATC CACAGTATCC AAAATAGCCA GGACATGAGG CAGATCAGTG ACGGAGAAAG AGAAGAATTA AATCTGACTG CAAACCGTTT GATGGGAAGA ACTCTCACCG TTGAAGTGTC AGTAGAAACA ATTAGAAACC CCCAGCAGCA AGAATCCCTA AAGCATGCCA CAAGGATTAT TGATGAGGTG GTCAATAAGT TTCTGGATGA TTTGGGAAAT GCCAAGAGTC ATTTAATGTC GCTCTACAGT GCATGTTCAT CTGAGGTGCC ACATGGGCCA GTTGATCAGA AGTTTCAATC CATAGTAATT GGCTGTGCTC TTGAAGATCA GAAGAAAATT AAGAGAAGAT TAGAGACTCT GCTTAGAAAT ATTGAAAACT CTGACAAGGC CATCAAGCTA TTAGAGCATT CTAAAGGAGC TGGTTCCAAA ACTCTGCAAC AAAATGCTGA AAGCAGATTC AATTAG
OMIM
603882
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of BAG2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BAG2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
20,189 Da
NCBI Official Full Name
Homo sapiens BCL2-associated athanogene 2, mRNA
NCBI Official Synonym Full Names
BCL2 associated athanogene 2
NCBI Official Symbol
NCBI Official Synonym Symbols
BAG-2; dJ417I1.2
  [Similar Products]
NCBI Protein Information
BAG family molecular chaperone regulator 2
UniProt Protein Name
BAG family molecular chaperone regulator 2
UniProt Synonym Protein Names
Bcl-2-associated athanogene 2
UniProt Gene Name
UniProt Synonym Gene Names
BAG-2  [Similar Products]
UniProt Entry Name
BAG2_HUMAN
NCBI Summary for BAG2
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
UniProt Comments for BAG2
BAG2: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 6p12.1-p11.2

Cellular Component: cytosol

Molecular Function: adenyl-nucleotide exchange factor activity; identical protein binding; protein binding

Biological Process: protein folding; protein metabolic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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