NP_001028522.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
89,406 Da
NCBI Official Full Name
B-cell scaffold protein with ankyrin repeats
NCBI Official Synonym Full Names
B cell scaffold protein with ankyrin repeats 1
NCBI Official Synonym Symbols
BANK; AVIEF; AI451642; A530094C12Rik [Similar Products]
NCBI Protein Information
B-cell scaffold protein with ankyrin repeats; B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript
UniProt Protein Name
B-cell scaffold protein with ankyrin repeats
UniProt Synonym Protein Names
Protein AVIEF
UniProt Entry Name
BANK1_MOUSE
UniProt Comments for BANK1
BANK1: Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. Genetic variations in BANK1 influence susceptibility to systemic lupus erythematosus (SLE). SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Molecular Function: protein binding
Biological Process: negative regulation of translational initiation; negative regulation of protein kinase B signaling cascade; B cell activation; positive regulation of MAPKKK cascade; negative regulation of B cell activation
Research Articles on BANK1
Precautions
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Disclaimer
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Pathways associated with BANK1 elisa kit
Diseases associated with BANK1 elisa kit
Organs/Tissues associated with BANK1 elisa kit
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