Q9NR55.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
14,468 Da
NCBI Official Full Name
Basic leucine zipper transcriptional factor ATF-like 3
NCBI Official Synonym Full Names
basic leucine zipper ATF-like transcription factor 3
NCBI Protein Information
basic leucine zipper transcriptional factor ATF-like 3
UniProt Protein Name
Basic leucine zipper transcriptional factor ATF-like 3
UniProt Synonym Protein Names
21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
UniProt Synonym Gene Names
UniProt Entry Name
BATF3_HUMAN
NCBI Summary for BATF3
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
UniProt Comments for BATF3
BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1q32.3
Molecular Function: protein binding; transcription corepressor activity; transcription factor activity
Biological Process: myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; response to virus; transcription from RNA polymerase II promoter
Research Articles on BATF3
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Pathways associated with BATF3 blocking peptide
Diseases associated with BATF3 blocking peptide
Organs/Tissues associated with BATF3 blocking peptide
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