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BBS10 cdna clone

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Catalog # MBS1265934
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
BBS10 cdna clone
Product Name

BBS10, cDNA Clone

Popular Item
Full Product Name

BBS10 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
atgatagtgg actgtgtttc cagtcatctc aaaaaaacag gagatggtgc aaaaacattt attatctttc tttgccattt gcttagagga cttcatgcaa tcacagacag agaaaaggat cctttgatgt gtgaaaacat tcaaacccat ggaaggcatt ggaaaaattg ttctcggtgg aaatttattt cccaggctct cctaacgttt cagacacaaa tattagacgg tattatggac cagtacctaa gtagacactt tttgtctatc ttttcgtctg ctaaagagag aacattgtgt aggagctctt tagagttgct cttagaagca tacttttgtg gaagagtggg aagaaataat cataaattta tttcacagtt gatgtgtgac tactttttca agtgtatgac ttgtaaaagt gggattggtg tatttgagtt agtggatgac cattttgtag agttgaatgt tggtgtcact ggccttcctg tttcagattc caggatcata gctggtcttg tgcttcagaa agatttttct gtgtaccgcc cagcagatgg tgacatgcga atggtgatag taacagaaac cattcagcct cttttttcca cttctggatc agagtttatt ctaaattcag aagcacagtt tcagacatct caattttgga ttatggaaaa gacaaaagca ataatgaaac atctacatag tcagaatgta aaattgctca tatctagtgt gaaacaacca gatttagtta gttattatgc aggggtgaat ggcatatcag tggttgagtg tttatcatca gaagaagttt ctcttatccg gaggatcatt ggtctttctc catttgtacc accacaggcc ttttcgcagt gtgaaatacc taacactgct ttggtgaaat tttgtaaacc tcttatcctt agatccaaaa gatatgttca tctaggcttg ataagcacat gtgcatttat accacactct atagttcttt gtggaccagt gcatggtctc attgaacaac atgaggatgc tttacatgga gcacttaaaa tgcttcggca attatttaaa gaccttgatc taaattacat gacacaaacc aatgaccaaa atggcacttc aagtcttttt atttataaga acagtggaga aagttatcaa gcaccagatc cgggtaatgg ctcaatacaa aggccttatc aggacacagt tgcagagaac aaagatgcat tggaaaaaac tcaaacatat ttaaaagtac attctaattt ggtaattcca gatgtagaat tagaaacata tattccgtat tcaaccccca cactgacacc aacagataca ttccaaacag ttgaaacgct gacatgtttg tctttggaaa gaaacaggct aactgattat tatgaaccat tactcaagaa caattccact gcttattcaa caaggggaaa tagaatagaa atttcttacg aaaatttaca ggtcacaaat attactagaa agggaagcat gttaccagtg agctgtaagt taccgaatat gggtacttcc cagagttacc tttcctcatc tatgccagct ggttgtgttt tgccagtagg tggtaatttt gatatcttgt tacattacta tcttctcaat tatgccaaaa aatgccatca atcagaagaa accatggtta gtatgataat agctaatgca cttttaggca ttcccaaagt cctttataaa tctaaaacag gaaagtacag ctttccacat acatatataa gagctgtcca tgcactgcaa accaatcaac ccttggtaag cagtcagaca ggtttggaat cagtaatggg taaataccag ctactaactt cagttcttca gtgtttgaca aaaatattaa ccattgacat ggtaatcact gttaagagac accctcagaa agttcacaat caagattcag aagatgaact ataa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of BBS10 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BBS10. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
80,838 Da
NCBI Official Full Name
Homo sapiens Bardet-Biedl syndrome 10, mRNA
NCBI Official Synonym Full Names
Bardet-Biedl syndrome 10
NCBI Official Symbol
BBS10  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
Bardet-Biedl syndrome 10 protein
UniProt Protein Name
Bardet-Biedl syndrome 10 protein
UniProt Gene Name
BBS10  [Similar Products]
UniProt Synonym Gene Names
C12orf58  [Similar Products]
UniProt Entry Name
NCBI Summary for BBS10
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010]
UniProt Comments for BBS10
BBS10: Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation. Defects in BBS10 are the cause of Bardet-Biedl syndrome type 10 (BBS10). Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Belongs to the TCP-1 chaperonin family.

Chromosomal Location of Human Ortholog: 12q21.2

Molecular Function: protein binding

Biological Process: chaperone-mediated protein complex assembly; photoreceptor cell maintenance; regulation of protein complex assembly; retinal homeostasis; sensory cilium biogenesis

Disease: Bardet-biedl Syndrome 10
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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