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BCAT1 cdna clone

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Catalog # MBS1267580
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
BCAT1 cdna clone
Product Name

BCAT1, cDNA Clone

Full Product Name

BCAT1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggattgca gtaacggatg ctccgcagag tgtaccggag aaggaggatc aaaagaggtg gtggggactt ttaaggctaa agacctaata gtcacaccag ctaccatttt aaaggaaaaa ccagacccca ataatctggt ttttggaact gtgttcacgg atcatatgct gacggtggag tggtcctcag agtttggatg ggagaaacct catatcaagc ctcttcagaa cctgtcattg caccctggct catcagcttt gcactatgca gtggaattat ttgaaggatt gaaggcattt cgaggagtag ataataaaat tcgactgttt cagccaaacc tcaacatgga tagaatgtat cgctctgctg tgagggcaac tctgccggta tttgacaaag aagagctctt agagtgtatt caacagcttg tgaaattgga tcaagaatgg gtcccatatt caacatctgc tagtctgtat attcgtccta cattcattgg aactgagcct tctcttggag tcaagaagcc taccaaagcc ctgctctttg tactcttgag cccagtggga ccttattttt caagtggaac ctttaatcca gtgtccctgt gggccaatcc caagtatgta agagcctgga aaggtggaac tggggactgc aagatgggag ggaattacgg ctcatctctt tttgcccaat gtgaagcagt agataatggg tgtcagcagg tcctgtggct ctatggagag gaccatcaga tcactgaagt gggaactatg aatctttttc tttactggat aaatgaagat ggagaagaag aactggcaac tcctccacta gatggcatca ttcttccagg agtgacaagg cggtgcattc tggacctggc acatcagtgg gacacagaac tcagcttgtt ttcaattaat ttgcctgatt ttctgcagtt catttacttt tga
OMIM
113520
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of BCAT1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BCAT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,131 Da
NCBI Official Full Name
Homo sapiens branched chain aminotransferase 1, cytosolic, mRNA
NCBI Official Synonym Full Names
branched chain amino acid transaminase 1
NCBI Official Symbol
BCAT1  [Similar Products]
NCBI Official Synonym Symbols
BCT1; PP18; BCATC; ECA39; MECA39; PNAS121
  [Similar Products]
NCBI Protein Information
branched-chain-amino-acid aminotransferase, cytosolic
UniProt Protein Name
Branched-chain-amino-acid aminotransferase, cytosolic
UniProt Synonym Protein Names
Protein ECA39
UniProt Gene Name
BCAT1  [Similar Products]
UniProt Synonym Gene Names
BCT1; ECA39; BCAT(c)  [Similar Products]
UniProt Entry Name
BCAT1_HUMAN
NCBI Summary for BCAT1
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
UniProt Comments for BCAT1
BCAT1: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.6.1.42; Transferase

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: cytosol; mitochondrion

Molecular Function: branched-chain-amino-acid transaminase activity; pyridoxal phosphate binding

Biological Process: aspartate biosynthetic process; branched chain family amino acid biosynthetic process; branched chain family amino acid catabolic process; cell proliferation; G1/S transition of mitotic cell cycle; leucine biosynthetic process; valine biosynthetic process
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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