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BD-2 (SAP1) recombinant protein

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Catalog # MBS691852
Unit / Price
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  0.005 mg  /  $200 +1 FREE 8GB USB
  0.02 mg  /  $340 +1 FREE 8GB USB
BD-2 (SAP1) recombinant protein
Product Name

BD-2 (SAP1), Recombinant Protein

Full Product Name

Human BD-2 (SAP1)

Product Synonym Names
Recombinant Human BD-2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
Chromosome Location
Chromosome: 8; NC_000008.11 (7414863..7416832, complement). Location: 8p23.1
OMIM
602215
3D Structure
ModBase 3D Structure for O15263
Host
E Coli
Species Reactivity
Human
Purity/Purification
> 95% by SDS-PAGE analyses
Form/Format
Lyophilized
Endotoxin Level
< 0.1 ng per g of BD-2
Biological Activity
Determined by its ability to chemoattract immature dendritic cells using a concentration of 10-100.0ng/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of BD-2 (SAP1) recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
BD-2 (SAP1) recombinant protein
Human beta-defensin-2 (BD-2) is an antimicrobial peptide which belongs to the distinct family of beta-defensins. Recent studies have shown that the beta-defensins are present in the human airways and may be relevant to the pathogenesis of cystic fibrosis lung disease. Human BD-2 is a 4.3 kDa protein containing 43 amino acid residues.
NCBI/Uniprot data below describe general gene information for BD-2 (SAP1). It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
4.3 kDa
NCBI Official Full Name
beta-defensin 4B
NCBI Official Synonym Full Names
defensin, beta 4B
NCBI Official Symbol
DEFB4B  [Similar Products]
NCBI Official Synonym Symbols
DEFB4P
  [Similar Products]
NCBI Protein Information
beta-defensin 4B; defensin, beta 4, pseudogene
UniProt Protein Name
Beta-defensin 4A
UniProt Synonym Protein Names
Beta-defensin 2; BD-2; hBD-2; Defensin, beta 2; Skin-antimicrobial peptide 1
UniProt Gene Name
DEFB4A  [Similar Products]
UniProt Synonym Gene Names
DEFB102; DEFB2; DEFB4; BD-2; hBD-2; SAP1  [Similar Products]
UniProt Entry Name
DFB4A_HUMAN
NCBI Summary for BD-2 (SAP1)
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Oct 2014]
UniProt Comments for BD-2 (SAP1)
Function: Has antibacterial activity

Potential.

Subcellular location: Secreted.

Tissue specificity: Expressed in the skin and respiratory tract.

Induction: By inflammation.

Sequence similarities: Belongs to the beta-defensin family. LAP/TAP subfamily.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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