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BDNF recombinant protein

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Catalog # MBS538322
Unit / Price
  0.002 mg  /  $180 +1 FREE 8GB USB
  0.01 mg  /  $310 +1 FREE 8GB USB
BDNF recombinant protein
Product Name

BDNF, Recombinant Protein

Also Known As

BDNF protein

Product Synonym Names
Brain Derived Neurotrophic Factor protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
247
Sequence
Region of BDNF protein correspond ing to amino acids MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR .
Host
Human
Purity/Purification
> 98% pure
Form/Format
Lyophilized from 20 mM Sodium Citrate buffer, pH 5.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
Protein Type
Recombinant
Biological Significance
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/tr kb. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues.
Bioactivity
Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 ug/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of BDNF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
BDNF recombinant protein
Purified recombinant Human BDNF protein
Applications Tested/Suitable for BDNF recombinant protein
User optimized
NCBI/Uniprot data below describe general gene information for BDNF. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27.0 kDa
NCBI Official Full Name
brain-derived neurotrophic factor
NCBI Official Synonym Full Names
brain-derived neurotrophic factor<
NCBI Official Symbol
bdnf-b  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
brain-derived neurotrophic factor
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with BDNF recombinant protein
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