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BDNF recombinant protein :: Brain Derived Neurotrophic Factor (BDNF) Recombinant Protein

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Catalog # MBS2009541 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $150 +1 FREE 8GB USB
  0.05 mg  /  $290 +1 FREE 8GB USB
  0.1 mg  /  $455 +1 FREE 8GB USB
  0.2 mg  /  $560 +1 FREE 8GB USB
  0.5 mg  /  $1,080 +1 FREE 8GB USB
  1 mg  /  $1,610 +2 FREE 8GB USB
Product Name

Brain Derived Neurotrophic Factor (BDNF), Recombinant Protein

Popular Item
Also Known As

Recombinant Brain Derived Neurotrophic Factor (BDNF)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
362
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF- NYLD AANMSMRVRR HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRG
Chromosome Location
Chromosome: 3; NC_005102.3 (107371329..107421908). Location: 3q33
3D Structure
ModBase 3D Structure for P23363
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Organism
Rattus norvegicus (Rat)
Expression System
Prokaryotic expression
Residues
Asn117~Gly248 (Accession # P23363) with N-terminal His-Tag
Subcellular Location
Secreted
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Predicted Isoelectric Point
9.6
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of BDNF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
BDNF recombinant protein
About the Marker: Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.
Ready-to-use: No need to heat, dilute or add reducing agents before use.
Applications Tested/Suitable for BDNF recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)

Sequence Information of BDNF recombinant protein
BDNF recombinant protein Sequence Information image
NCBI/Uniprot data below describe general gene information for BDNF. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16.6kDa
NCBI Official Full Name
brain-derived neurotrophic factor isoform 1
NCBI Official Synonym Full Names
brain-derived neurotrophic factor
NCBI Official Symbol
NCBI Protein Information
brain-derived neurotrophic factor; brain derived neurotrophic factor; brain derived neurothrophic factor
UniProt Protein Name
Brain-derived neurotrophic factor
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
BDNF_RAT
NCBI Summary for BDNF
plays a role in the development of hippocampal long term potentiation; involved in regulation of synaptic plasticity [RGD, Feb 2006]
UniProt Comments for BDNF
Function: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS

By similarity.

Subunit structure: Monomers and homodimers. Binds to NTRK2/TRKB

By similarity.

Subcellular location: Secreted.

Post-translational modification: Converted into mature BDNF by plasmin (PLG)

By similarity.

Sequence similarities: Belongs to the NGF-beta family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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