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becn1 recombinant protein :: Beclin-1 (becn1) Recombinant Protein

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Catalog # MBS1305515
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $860 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $935 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,155 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,165 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,270 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,275 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,410 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,435 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,685 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,930 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,190 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,280 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,280 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,385 +4 FREE 8GB USB
becn1 recombinant protein
Product Name

Beclin-1 (becn1), Recombinant Protein

Full Product Name

Recombinant Xenopus laevis Beclin-1 (becn1)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-445aa, full length protein
Sequence
METSKSSTMQ VSFVCQRCSQ PLKLDTSFKI LDKVTMQELT APLVTTAAVK PGDIQEVDSN IEETFAENRT DGVSRRLIPP ARMMSTESAT SFTLIGEASD GGTMENLSRR LKVTGDLFDI MSGQTDVDHP LCEECTDTLL DQLDTQLNIT ENECQNYKRC LEILERMNED DKEKLEAKLK ELAEDEERLI QELEEVERNR ELVAKDIEKV REEAERLEQE EARYQKEYSE FKRQQLELDD DLKSVENQMR YAQIQLDKLK KTNVFNATFH IWHSGQFGTI NNFRLGRLPS VPVEWNEINA AWGQTVLLLH ALANKMGLQF QRYRLVPFGN HSYLESLTDK SKELPLYCSG GLRFFWDNKF DHAMVAFLDC VQQFKEEVEK GDTGFCLPYR MDVDKGKIED TGGSGGSYSI KTQFNSEEQW TKALKFMLTN LKWGLAWVSS QFYNK
3D Structure
ModBase 3D Structure for Q6GP52
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Xenopus laevis (African clawed frog)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of becn1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for becn1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
51,294 Da
NCBI Official Full Name
beclin-1
NCBI Official Synonym Full Names
beclin 1, autophagy related L homeolog
NCBI Official Symbol
becn1.L  [Similar Products]
NCBI Official Synonym Symbols
becn1; beclin1
  [Similar Products]
NCBI Protein Information
beclin-1
UniProt Protein Name
Beclin-1
Protein Family
UniProt Gene Name
becn1  [Similar Products]
UniProt Comments for becn1
Plays a central role in autophagy (). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms (). Involved in endocytosis including endosome formation in neuronal cells ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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