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BIRC5 peptide :: Survivin / BIRC5 Peptide

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Catalog # MBS425577
Unit / Price
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  0.1 mg  /  $190 +1 FREE 8GB USB
BIRC5 peptide
Product Name

Survivin / BIRC5, Peptide

Full Product Name

Survivin / BIRC5 Immunizing Peptide

Product Synonym Names
BIRC5; survivin; API4; EPR-1; baculoviral IAP repeat-containing 5 (survivin); apoptosis inhibitor 4; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing protein 5; survivin variant 3 alpha; Survivin; Survivin / BIRC5
Product Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
CVRRAIEQLA AMD
OMIM
603352
Species Reactivity
Human, Cat, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of BIRC5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BIRC5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
Manufactured in an ISO 9001:2015 Certified Laboratory.NP_001012271.1[Other Products]
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
8,490 Da
NCBI Official Full Name
baculoviral IAP repeat-containing protein 5 isoform 1
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 5
NCBI Official Symbol
BIRC5  [Similar Products]
NCBI Official Synonym Symbols
API4; EPR-1
  [Similar Products]
NCBI Protein Information
baculoviral IAP repeat-containing protein 5
UniProt Protein Name
Baculoviral IAP repeat-containing protein 5
UniProt Synonym Protein Names
Apoptosis inhibitor 4; Apoptosis inhibitor survivin
UniProt Gene Name
BIRC5  [Similar Products]
UniProt Synonym Gene Names
API4; IAP4  [Similar Products]
UniProt Entry Name
BIRC5_HUMAN
NCBI Summary for BIRC5
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for BIRC5
Survivin: an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: centriole; chromosome, pericentric region; cytoplasm; cytoplasmic microtubule; cytosol; interphase microtubule organizing center; microtubule; midbody; nuclear chromosome; nucleoplasm; nucleus; spindle; spindle microtubule

Molecular Function: caspase inhibitor activity; chaperone binding; cobalt ion binding; cofactor binding; cysteine protease inhibitor activity; enzyme binding; identical protein binding; metal ion binding; microtubule binding; protein binding; protein heterodimerization activity; protein homodimerization activity; Ran GTPase binding; tubulin binding; ubiquitin-protein ligase activity; zinc ion binding

Biological Process: cell division; cytokinesis; establishment of chromosome localization; G2/M transition of mitotic cell cycle; mitosis; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of exit from mitosis; positive regulation of mitotic cell cycle; protein amino acid phosphorylation; protein complex localization; protein sumoylation; protein ubiquitination; regulation of apoptosis; regulation of signal transduction; sister chromatid cohesion; spindle checkpoint; transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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