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BLVRA recombinant protein :: Biliverdin reductase A Recombinant Protein

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Catalog # MBS203378
Unit / Price
  0.1 mg  /  $255 +1 FREE 8GB USB
  0.5 mg  /  $535 +1 FREE 8GB USB
SDS-Page
Product Name

Biliverdin reductase A (BLVRA), Recombinant Protein

Popular Item
Also Known As

Biliverdin reductase A, 3-296aa, Human, E Coli (Bioactivity Validated)

Product Synonym Names
Biliverdin reductase A; BLVR; BVR; BVRA; BLVRA; Biliverdin reductase A Biliverdin IX alpha reductase; BLVR A; BVR A; Zinc metalloprotein.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
296
Sequence
MAEPERKFGV VVVGVGRAGS VRMRDLRNPH PSSAFLNLIG FVSRRELGSI DGVQQISLED ALSSQEVEVA YICSESSSHE DYIRQFLNAG KHVLVEYPMT LSLAAAQELW ELAEQKGKVL HEEHVELLME EFAFLKKEVV GKDLLKGSLL FTAGPLEEER FGFPAFSGIS RLTWLVSLFG ELSLVSATLE ERKEDQYMKM TVCLETEKKS PLSWIEEKGP GLKRNRYLSF HFKSGSLENV PNVGVNKNIF LKDQNIFVQK LLGQFSEKEL AAEKKRILHC LGLAEEIQKY CCSRK
OMIM
U34877 mRNA
3D Structure
ModBase 3D Structure for P53004
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Biological Activity
Specific activity is > 450 pmol/min/ug, and is defined as the amount of enzyme that catalyze the reduction 1.0 pmole of biliverdin of NADPH per minute at pH 8.8 at 25C.
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of BLVRA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
BLVRA recombinant protein
BLVRA, also known as biliverdin reductase A, belongs to the gfo/idh/mocA family. This protein is an enzyme that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. (Bilirubin + NAD (P)+ = biliverdin + NAD (P)H) Recombinant BLVRA protein was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for BLVRA recombinant protein
Applications Tested/Suitable for BLVRA recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for BLVRA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33.3 kDa (295aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher) [Similar Products]
NCBI Official Full Name
biliverdin reductase A
NCBI Official Synonym Full Names
biliverdin reductase A
NCBI Official Symbol
BLVRA  [Similar Products]
NCBI Official Synonym Symbols
BVR; BLVR; BVRA
  [Similar Products]
NCBI Protein Information
biliverdin reductase A
UniProt Protein Name
Biliverdin reductase A
UniProt Synonym Protein Names
Biliverdin-IX alpha-reductase
Protein Family
UniProt Gene Name
BLVRA  [Similar Products]
UniProt Synonym Gene Names
BLVR; BVR; BVR A  [Similar Products]
NCBI Summary for BLVRA
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011]
UniProt Comments for BLVRA
Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
Product References and Citations for BLVRA recombinant protein
Kravets A., et al. (2004) J Biol Chem. 279 (19):19916-23.; Franklin E., et al. (2007) Biochem J. 405 (1):61-7.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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