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anti-BNP antibody :: Mouse anti-Human BNP Antibody

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Catalog # MBS355823
Unit / Price
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  1 mg  /  $420 +1 FREE 8GB USB
anti-BNP antibody
Product Name

BNP, Antibody

Popular Item
Full Product Name

Anti-BNP Antibody (Detection Ab)

Product Synonym Names
Brain natriuretic peptide, BNP mAb (Mouse anti-human, clone # 2D6)-Capture Ab
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
M31776 Genomic DNA
3D Structure
ModBase 3D Structure for P16860
Isotype
IgG2b
Clone Number
2D6
Host
Mouse
Species Reactivity
Human
Purity/Purification
>95% by HPLC & SDS-PAGE
Form/Format
Liquid
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative.
Preparation and Storage
Aliquot and store at -20┬░C for long term (at least one year).

Avoid repeated freeze and thaw cycles.
Other Notes
Small volumes of anti-BNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BNP antibody
Background: Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide or natriuretic peptide B) is a 32-amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). BNP is secreted attached to a 76┬ľamino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. BNP is synthesized as a 134-amino acid preprohormone (preproBNP), encoded by the human gene NPPB.
Applications Tested/Suitable for anti-BNP antibody
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), Flow Fluorenscence Immunmicrobeads Assay (FFIA)
Application Notes for anti-BNP antibody
Other applications have not been tested

The optimal dilutions should not be determined by end user.

Matched antibody pair:

Capture Ab: BNP: mAb (clone #B4)
Detection Ab: BNP mAb ( clone#2D6)
NCBI/Uniprot data below describe general gene information for BNP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
natriuretic peptides B preproprotein
NCBI Official Synonym Full Names
natriuretic peptide B
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
natriuretic peptides B
UniProt Protein Name
Natriuretic peptides B
UniProt Synonym Protein Names
Gamma-brain natriuretic peptide
UniProt Gene Name
UniProt Synonym Gene Names
BNP(1-32); BNP-32  [Similar Products]
NCBI Summary for BNP
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
UniProt Comments for BNP
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Product References and Citations for anti-BNP antibody
1. Ziskoven D, Forssmann WG, Holthausen U, Menz G, Addicks K, Rippegater G (1989). "Calcium Calmodulin antagonists Influences the release of Cardiodilatin/ANP from Atrial Cardiocytes". In Kaufmann W, Wambach G. Handbook Endocrinology of the Heart. Berlin: Verlag: Springer. pp. 233-4.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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