NP_000614.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
41,441 Da
NCBI Official Full Name
B2 bradykinin receptor
NCBI Official Synonym Full Names
bradykinin receptor B2
NCBI Protein Information
B2 bradykinin receptor; BK-2 receptor
UniProt Protein Name
B2 bradykinin receptor
UniProt Synonym Gene Names
UniProt Entry Name
BKRB2_HUMAN
NCBI Summary for BDKRB2
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008]
UniProt Comments for BDKRB2
BKR2: a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 14q32.1-q32.2
Cellular Component: integral to plasma membrane; plasma membrane; endosome
Molecular Function: bradykinin receptor activity; protein binding; protease binding; protein heterodimerization activity; type 1 angiotensin receptor binding; phosphoinositide phospholipase C activity
Biological Process: vasoconstriction; metabolic process; blood circulation; negative regulation of peptidyl-serine phosphorylation; arachidonic acid secretion; vasodilation; response to salt stress; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; smooth muscle contraction; cell surface receptor linked signal transduction; regulation of vasoconstriction; regulation of vascular permeability; inflammatory response; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on BDKRB2
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Products associated with BDKRB2 elisa kit
Pathways associated with BDKRB2 elisa kit
Diseases associated with BDKRB2 elisa kit
Organs/Tissues associated with BDKRB2 elisa kit
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