NP_116172.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,837 Da
NCBI Official Full Name
carbonyl reductase family member 4
NCBI Official Synonym Full Names
carbonyl reductase 4
NCBI Official Synonym Symbols
NCBI Protein Information
carbonyl reductase family member 4; carbonic reductase 4; quinone reductase CBR4; 3-oxoacyl-[acyl-carrier-protein] reductase; short chain dehydrogenase/reductase family 45C, member 1
UniProt Protein Name
Carbonyl reductase family member 4
UniProt Synonym Protein Names
3-oxoacyl-[acyl-carrier-protein] reductase (EC:1.1.1.-); Quinone reductase CBR4
UniProt Entry Name
CBR4_HUMAN
UniProt Comments for CBR4
CBR4: The heteroteramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Oxidoreductase; EC 1.-.-.-; EC 1.1.1.-
Chromosomal Location of Human Ortholog: 4q32.3
Cellular Component: mitochondrial matrix
Molecular Function: protein binding; NAD(P)H dehydrogenase (quinone) activity; NADPH dehydrogenase (quinone) activity; quinone binding
Biological Process: fatty acid biosynthetic process; protein homotetramerization
Research Articles on CBR4
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Diseases associated with CBR4 elisa kit
Organs/Tissues associated with CBR4 elisa kit
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