NP_001106171.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,726 Da
NCBI Official Full Name
cytohesin-2 isoform 2
NCBI Official Synonym Full Names
cytohesin 2
NCBI Protein Information
cytohesin-2; mSec7-2; SEC7 homolog B; ARF nucleotide-binding site opener; pleckstrin homology, Sec7 and coiled-coil domains 2; PH, SEC7 and coiled-coil domain-containing protein 2
UniProt Protein Name
Cytohesin-2
UniProt Synonym Protein Names
ARF nucleotide-binding site opener; Protein ARNO; PH, SEC7 and coiled-coil domain-containing protein 2; CLM2; SEC7 homolog B; mSec7-2
UniProt Synonym Gene Names
UniProt Entry Name
CYH2_MOUSE
UniProt Comments for CYTH2
cytohesin 2: Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, ARF
Cellular Component: ruffle; membrane; cytoplasm; plasma membrane
Molecular Function: protein binding; guanyl-nucleotide exchange factor activity; lipid binding; ARF guanyl-nucleotide exchange factor activity
Biological Process: regulation of cell adhesion; regulation of ARF protein signal transduction; positive regulation of GTPase activity
Research Articles on CYTH2
Precautions
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Disclaimer
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Pathways associated with CYTH2 elisa kit
Diseases associated with CYTH2 elisa kit
Organs/Tissues associated with CYTH2 elisa kit
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