BC107091
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
27,317 Da
NCBI Official Full Name
Homo sapiens B and T lymphocyte associated, mRNA
NCBI Official Synonym Full Names
B and T lymphocyte associated
NCBI Official Synonym Symbols
NCBI Protein Information
B- and T-lymphocyte attenuator
UniProt Protein Name
B- and T-lymphocyte attenuator
UniProt Synonym Protein Names
B- and T-lymphocyte-associated protein; CD_antigen: CD272
UniProt Entry Name
BTLA_HUMAN
NCBI Summary for BTLA
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
UniProt Comments for BTLA
BTLA: Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q13.2
Cellular Component: plasma membrane
Biological Process: T cell costimulation
Research Articles on BTLA
Precautions
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Disclaimer
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Pathways associated with BTLA cdna clone
Diseases associated with BTLA cdna clone
Organs/Tissues associated with BTLA cdna clone
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