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C1qa recombinant protein :: Complement C1q subcomponent subunit A (C1qa) Recombinant Protein

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Catalog # MBS966734
Unit / Price
  0.01 mg (E-Coli)  /  $195 +1 FREE 8GB USB
  0.01 mg (Yeast)  /  $195 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $255 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
  0.1 mg (Yeast)  /  $415 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $660 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $915 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,090 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,155 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,155 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,665 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,730 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,760 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,225 +2 FREE 8GB USB
SDS-PAGE
Product Name

Complement C1q subcomponent subunit A (C1qa), Recombinant Protein

Popular Item
Also Known As

Recombinant Mouse Complement C1q subcomponent subunit A (C1qa)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS966734 COA
Sequence Positions
23-245. Full length of the mature protein.
Sequence Length
245
Sequence
EDVCRAPNGK DGAPGNPGRP GRPGLKGERG EPGAAGIRTG IRGFKGDPGE SGPPGKPGNV GLPGPSGPLG DSGPQGLKGV KGNPGNIRDQ PRPAFSAIRQ NPMTLGNVVI FDKVLTNQES PYQNHTGRFI CAVPGFYYFN FQVISKWDLC LFIKSSSGGQ PRDSLSFSNT NNKGLFQVLA GGTVLQLRRG DEVWIEKDPA KGRIYQGTEA DSIFSGFLIF PSA
3D Structure
ModBase 3D Structure for P98086
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of C1qa recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
C1qa recombinant protein
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complent system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

C1qa recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for C1qa. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39.5kD
NCBI Official Full Name
complement C1q subcomponent subunit A
NCBI Official Synonym Full Names
complement component 1, q subcomponent, alpha polypeptide
NCBI Official Symbol
NCBI Official Synonym Symbols
C1q; AI255395
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NCBI Protein Information
complement C1q subcomponent subunit A
UniProt Protein Name
Complement C1q subcomponent subunit A
UniProt Gene Name
UniProt Entry Name
C1QA_MOUSE
UniProt Comments for C1qa
C1QA: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2 )-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: collagen; extracellular region

Molecular Function: protein binding

Biological Process: complement activation, classical pathway; immune system process; innate immune response
Product References and Citations for C1qa recombinant protein
Gene expression of the A- and B-chain of mouse C1q in different tissues and the characterization of the recombinant A-chain.Petry F., Reid K.B.M., Loos M.J. Immunol. 147:3988-3993(1991) The mouse C1q genes are clustered on chromosome 4 and show conservation of gene organization.Petry F., McClive P.J., Botto M., Morley B.J., Morahan G., Loos M.Immunogenetics 43:370-376(1996) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Proteome-wide characterization of N-glycosylation events by diagonal chromatography.Ghesquiere B., Van Damme J., Martens L., Vandekerckhove J., Gevaert K.J. Proteome Res. 5:2438-2447(2006)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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