NP_001121898.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
34,280 Da
NCBI Official Full Name
AP-1 complex-associated regulatory protein isoform b
NCBI Official Synonym Full Names
adaptor-related protein complex 1 associated regulatory protein
NCBI Official Synonym Symbols
2C18; GBAR; C4orf16; PRO0971; gamma-BAR [Similar Products]
NCBI Protein Information
AP-1 complex-associated regulatory protein; gadkin; gamma-A1-adaptin and kinesin interactor; gamma-1-adaptin brefeldin A resistance protein; gamma1-adaptin brefeldin A resistance protein, gamma-BAR; adapter-related protein complex 1-associated regulatory protein
UniProt Protein Name
AP-1 complex-associated regulatory protein
UniProt Synonym Protein Names
2c18; Adaptor-related protein complex 1-associated regulatory protein; Gamma-1-adaptin brefeldin A resistance protein; GBAR; Gamma-BAR; Gamma-A1-adaptin and kinesin interactor; Gadkin
UniProt Synonym Gene Names
UniProt Entry Name
AP1AR_HUMAN
UniProt Comments for C4orf16
AP1AR: Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1- adaptin attenuates the release of the AP-1 complex from membranes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 4q25
Cellular Component: Golgi apparatus; transport vesicle; early endosome; late endosome
Molecular Function: kinesin binding
Biological Process: protein transport; negative regulation of receptor recycling; vesicle targeting, trans-Golgi to endosome
Research Articles on C4orf16
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