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C9 cdna clone

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Catalog # MBS1278424
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
C9 cdna clone
Product Name

C9, cDNA Clone

Popular Item
Also Known As

C9 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1680
Sequence
atgtcagcct gccggagctt tgcagttgca atctgcattt tagaaataag catcctcaca gcacagtaca cgaccagtta tgacccagag ctaacagaaa gcagtggctc tgcatcacac atagactgca gaatgagccc ctggagtgaa tggtcacaat gcgatccttg tctcagacaa atgtttcgtt caagaagcat tgaggtcttt ggacaattta atgggaaaag atgcaccgac gctgtgggag acagacgaca gtgtgtgccc acagagccct gtgaggatgc tgaggatgac tgcggaaatg actttcaatg cagtacaggc agatgcataa agatgcgact tcggtgtaat ggtgacaatg actgcggaga cttttcagat gaggatgatt gtgaaagtga gccccgtccc ccctgcagag acagagtggt agaagagtct gagctggcac gaacagcagg ctatgggatc aacattttag ggatggatcc cctaagcaca ccttttgaca atgagttcta caatggactc tgtaaccggg atcgggatgg aaacactctg acatactacc gaagaccttg gaacgtggct tctttgatct atgaaaccaa aggcgagaaa aatttcagaa ccgaacatta cgaagaacaa attgaagcat ttaaaagtat catccaagag aagacatcaa attttaatgc agctatatct ctaaaattta cacccactga aacaaataaa gctgaacaat gttgtgagga aacagcctcc tcaatttctt tacatggcaa gggtagtttt cggttttcat attccaaaaa tgaaacttac caactatttt tgtcatattc ttcaaagaag gaaaaaatgt ttctgcatgt gaaaggagaa attcatctgg gaagatttgt aatgagaaat cgcgatgttg tgctcacaac aacttttgtg gatgatataa aagctttgcc aactacctat gaaaagggag aatattttgc ctttttggaa acctatggaa ctcactacag tagctctggg tctctaggag gactctatga actaatatat gttttggata aagcttccat gaagcggaaa ggtgttgaac taaaagacat aaagagatgc cttgggtatc atctggatgt atctctggct ttctctgaaa tctctgttgg agctgaattt aataaagatg attgtgtaaa gaggggagag ggtagagctg taaacatcac cagtgaaaac ctcatagatg atgttgtttc actcataaga ggtggaacca gaaaatatgc atttgaactg aaagaaaagc ttctccgagg aaccgtgatt gatgtgactg actttgtcaa ctgggcctct tccataaatg atgctcctgt tctcattagt caaaaactgt ctcctatata taatctggtt ccagtgaaaa tgaaaaatgc acacctaaag aaacaaaact tggaaagagc cattgaagac tatatcaatg aatttagtgt aagaaaatgc cacacatgcc aaaatggagg tacagtgatt ctaatggatg gaaagtgttt gtgtgcctgc ccattcaaat ttgagggaat tgcctgtgaa atcagtaaac aaaaaatttc tgaaggattg ccagccctag agttccccaa tgaaaaatag
OMIM
120940
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of C9 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
Molecular Weight
63,173 Da
NCBI Official Full Name
Homo sapiens complement component 9, mRNA
NCBI Official Synonym Full Names
complement C9
NCBI Official Symbol
NCBI Official Synonym Symbols
C9D; ARMD15
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NCBI Protein Information
complement component C9
UniProt Protein Name
Complement component C9
Protein Family
UniProt Gene Name
UniProt Entry Name
CO9_HUMAN
NCBI Summary for C9
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
UniProt Comments for C9
C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Extracellular matrix; Membrane protein, multi-pass; Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: cytoplasm; extracellular region; integral to plasma membrane; plasma membrane

Biological Process: hemolysis by symbiont of host red blood cells; regulation of complement activation

Disease: Complement Component 9 Deficiency; Macular Degeneration, Age-related, 15
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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