NP_001005747
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit beta-4 isoform a
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit beta 4
NCBI Official Synonym Symbols
EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4 [Similar Products]
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-4
UniProt Protein Name
Voltage-dependent L-type calcium channel subunit beta-4
UniProt Synonym Protein Names
Calcium channel voltage-dependent subunit beta 4
UniProt Synonym Gene Names
UniProt Entry Name
CACB4_HUMAN
NCBI Summary for CACNB4
This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016]
Research Articles on CACNB4
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Pathways associated with CACNB4 blocking peptide
Diseases associated with CACNB4 blocking peptide
Organs/Tissues associated with CACNB4 blocking peptide
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