NP_055220.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,579 Da
NCBI Official Full Name
voltage-dependent calcium channel gamma-4 subunit
NCBI Official Synonym Full Names
calcium channel, voltage-dependent, gamma subunit 4
NCBI Protein Information
voltage-dependent calcium channel gamma-4 subunit; TARP gamma-4; transmembrane AMPAR regulatory protein gamma-4; neuronal voltage-gated calcium channel gamma-4 subunit
UniProt Protein Name
Voltage-dependent calcium channel gamma-4 subunit
UniProt Synonym Protein Names
Neuronal voltage-gated calcium channel gamma-4 subunit; Transmembrane AMPAR regulatory protein gamma-4; TARP gamma-4
UniProt Synonym Gene Names
UniProt Entry Name
CCG4_HUMAN
NCBI Summary for CACNG4
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]
UniProt Comments for CACNG4
CACNG4: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Protein type: Channel, calcium; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q24
Cellular Component: integral to plasma membrane; plasma membrane; voltage-gated calcium channel complex
Molecular Function: voltage-gated calcium channel activity
Biological Process: membrane depolarization; synaptic transmission; transport; transmission of nerve impulse
Research Articles on CACNG4
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Products associated withCACNG4 elisa kit
Pathways associated with CACNG4 elisa kit
Diseases associated with CACNG4 elisa kit
Organs/Tissues associated with CACNG4 elisa kit
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